Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Sana Biotechnology Closes Upsized Public Offering and Underwriters' Option
Details : Proceeds will focus on developing SC291, an allogeneic CD19-directed CAR T cell therapy for relapsed/refractory B-cell malignancies, including Non-Hodgkin lymphoma & Chronic lymphocytic leukemia.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 12, 2024
Sana Biotechnology Announces Pricing of Upsized Public Offering
Details : Proceeds will focus on developing SC291, an allogeneic CD19-directed CAR T cell therapy for relapsed/refractory B-cell malignancies, including Non-Hodgkin lymphoma & Chronic lymphocytic leukemia.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 08, 2024
Sana Biotechnology Announces Proposed Public Offering of Common Stock
Details : Proceeds will focus on developing SC291, an allogeneic CD19-directed CAR T cell therapy for relapsed/refractory B-cell malignancies, including Non-Hodgkin lymphoma & Chronic lymphocytic leukemia.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 07, 2024
Lead Product(s) : SC262
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SC262 is a hypoimmune, CD22-directed allogeneic CAR T cell therapy derived from healthy donor CD4+ and CD8+ T cells. It is under preclinical development for the treatment of patients with relapsed or refractory B-cell malignancies.
Brand Name : SC262
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 05, 2023
Lead Product(s) : SC262
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : UP421
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : UP421 is an allogeneic, primary islet cell therapy engineered with Sana’s hypoimmune (HIP) technology, which is being evaluated for the treatment of patients with type 1 diabetes.
Brand Name : UP421
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 17, 2023
Lead Product(s) : UP421
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SC291
Therapeutic Area : Nephrology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SC291, a Hypoimmune-modified, CD19-directed Allogeneic CAR T Therapy, for Patients with Lupus Nephritis, Extrarenal Lupus, and ANCA-associated Vasculitis.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 09, 2023
Lead Product(s) : SC291
Therapeutic Area : Nephrology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SC291
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SC291 is a CD19-targeted allogeneic CAR T cell therapy developed using Sana’s hypoimmune platform. SC291 may result in longer CAR T cell persistence and a higher rate of durable complete responses for patients with B-cell lymphomas or leukemias.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 26, 2023
Lead Product(s) : SC291
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SG295
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The company expects to study SG295, an in vivo CAR T with CD8-targeted fusosome delivery of a CD19-targeted CAR, in B cell malignancies. With increased potency, SG295 has the potential to generate a comparable no. of CAR T cells to current ex vivo manufa...
Brand Name : SG295
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 11, 2022
Lead Product(s) : SG295
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SC291
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The SC291 preclinical data demonstrate these hypoimmunogenic CAR T cells are able to evade both the innate and adaptive arms of the immune system while retaining their antitumor activity.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 03, 2022
Lead Product(s) : SC291
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SC291
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : First demonstration of SC291, survival of allogeneic islet cells, cardiomyocytes, and retinal pigment epithelium cells transplanted into an immunocompetent non-human primate model without any immune suppression.
Brand Name : SC291
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 17, 2022
Lead Product(s) : SC291
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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