Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ST-501
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Genentech
Deal Size : $1,950.0 million
Deal Type : Licensing Agreement
Sangamo Therapeutics Announces License Agreement with Genentech for Genomic Medicines
Details : Under the license agreement, Genentech will gain the rights of ST-501, which is being evaluated in the early-stage clinical trial studies for the treatment of tauopathies.
Brand Name : ST-501
Molecule Type : Cell and Gene therapy
Upfront Cash : $50.0 million
August 06, 2024
Lead Product(s) : ST-501
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Genentech
Deal Size : $1,950.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Barclays
Deal Size : $24.0 million
Deal Type : Public Offering
Sangamo Therapeutics Announces Pricing of $24.0 Million Registered Direct Offering
Details : Sangamo anticipates using net proceeds to fund the development of its neurology-focused genomic medicines pipeline, targeting the SCN9A gene for peripheral neuropathic pain.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 22, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Barclays
Deal Size : $24.0 million
Deal Type : Public Offering
Lead Product(s) : STAC-BBB
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sangamo Announces Data on AAV Capsid Showing Blood-Brain Barrier Penetration
Details : STAC-BBB is a proprietary neurotropic AAV capsid showing blood-brain barrier penetration in preclinical studies, evaluated for treating prion disease and tauopathy.
Brand Name : STAC-BBB
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 13, 2024
Lead Product(s) : STAC-BBB
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sangamo Announces FDA Alignment on Pathway for ST-920 in Fabry Disease Approval
Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A. It is being developed for the treatment of Fabry Disease.
Brand Name : ST-920
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 12, 2024
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sangamo Therapeutics Announces Updated Phase 1/2 STAAR Study Data in Fabry Disease
Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A. It is being evaluated in phase 1/2 clinical trials for the treatment of Fabry Disease.
Brand Name : ST-920
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 05, 2024
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Epigenetic Medicine
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Chroma Medicine
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Chroma will evaluate novel Sangamo zinc finger proteins (ZFPs) for specified collaboration targets outside of the central nervous system, for the development of epigenetic medicines.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 20, 2023
Lead Product(s) : Epigenetic Medicine
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Chroma Medicine
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Adeno-associated Virus Gene Therapy
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Prevail Therapeutics
Deal Size : $1,190.0 million
Deal Type : Agreement
Details : Under the agreement, Prevail has been granted rights to evaluate certain proprietary adeno-associated virus (AAV) capsids developed by Sangamo and may exercise certain options to license these capsids for multiple undisclosed neurological targets.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 17, 2023
Lead Product(s) : Adeno-associated Virus Gene Therapy
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Prevail Therapeutics
Deal Size : $1,190.0 million
Deal Type : Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Recipient : Voyager Therapeutics, Inc
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Sangamo has received a non-exclusive license to combine a Voyager TRACER capsid with Sangamo’s ZF-TRs (zinc finger transcriptional regulator) designed to treat prion disease.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 29, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Recipient : Voyager Therapeutics, Inc
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A that aims to deliver a working copy of the GLA gene to the liver so that liver cells can start producing functional α-Gal A in patients with fabry ...
Brand Name : ST-920
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 22, 2023
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A that aims to deliver a working copy of the GLA gene to the liver so that liver cells can start producing functional α-Gal A in patients with fabry ...
Brand Name : ST-920
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 22, 2023
Lead Product(s) : Isaralgagene Civaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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