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    [{"orgOrder":0,"company":"Sangamo Therapeutics","sponsor":"Biogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Collaboration","leadProduct":"ST-501","moa":"Tau aggregation","graph1":"Neurology","graph2":"Preclinical","graph3":"Sangamo Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sangamo Therapeutics \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Sangamo Therapeutics \/ Biogen"},{"orgOrder":0,"company":"Sangamo Therapeutics","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"Sangamo 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                            01

                            Sangamo Therapeutics

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                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sangamo Updates Phase 1/2 STAAR Study, Showing Fabry Disease Benefits

                            Details : ST-920 (isaralgagene civaparvovec) is an AAV2/6 human alpha-Gal A gene therapy product candidate in patients for the treatment of Fabry disease.

                            Product Name : ST-920

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 06, 2025

                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Sangamo Therapeutics

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                            Lead Product(s) : Giroctocogene fitelparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : $125.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Sangamo Shares Plunge Pfizer Ends Hemophilia a Gene Therapy Deal

                            Details : Sangamo will regain development and commercialization rights to PF-07055480 (giroctocogene fitelparvovec), an investigational gene therapy for adults with moderately severe to severe hemophilia A.

                            Product Name : PF-07055480

                            Product Type : Cell and Gene therapy

                            Upfront Cash : $70.0 million

                            December 31, 2024

                            Lead Product(s) : Giroctocogene fitelparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : $125.0 million

                            Deal Type : Termination

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                            03

                            Sangamo Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Sponsor : Astellas Pharma

                            Deal Size : $1,320.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Astellas, Sangamo Partner on Genomic Medicines for Neurological Disease Via Capsid Tech

                            Details : Under the license agreement, Astellas will leverage Sangamo's novel proprietary neurotropic adeno-associated virus (AAV) capsid, STAC-BBB for the treatment of neurological diseases.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $20.0 million

                            December 19, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Sponsor : Astellas Pharma

                            Deal Size : $1,320.0 million

                            Deal Type : Licensing Agreement

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                            04

                            Sangamo Therapeutics

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                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sangamo Announces FDA Alignment on Pathway for ST-920 in Fabry Disease Approval

                            Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A. It is being developed for the treatment of Fabry Disease.

                            Product Name : ST-920

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 02, 2024

                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Sangamo Therapeutics

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                            Lead Product(s) : ST-503

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sangamo Gets FDA IND Clearance for ST-503 in Chronic Neuropathic Pain Treatment

                            Details : ST-503 is an investigational epigenetic regulator for the treatment of intractable pain due to idiopathic small fiber neuropathy (iSFN).

                            Product Name : ST-503

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            November 19, 2024

                            Lead Product(s) : ST-503

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Sangamo Therapeutics

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                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sangamo Aligns with FDA on ST-920 Approval Pathway for Fabry, BLA Due 2025

                            Details : ST-920 (isaralgagene civaparvovec) is an AAV2/6 human alpha-Gal A gene therapy product candidate in patients for the treatment of Fabry disease.

                            Product Name : ST-920

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 22, 2024

                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Sangamo Therapeutics

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                            Lead Product(s) : ST-501

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Genentech

                            Deal Size : $1,950.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Sangamo Therapeutics Announces License Agreement with Genentech for Genomic Medicines

                            Details : Under the license agreement, Genentech will gain the rights of ST-501, which is being evaluated in the early-stage clinical trial studies for the treatment of tauopathies.

                            Product Name : ST-501

                            Product Type : Cell and Gene therapy

                            Upfront Cash : $50.0 million

                            June 08, 2024

                            Lead Product(s) : ST-501

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Genentech

                            Deal Size : $1,950.0 million

                            Deal Type : Licensing Agreement

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                            08

                            Sangamo Therapeutics

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                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sangamo Therapeutics Announces Updated Phase 1/2 STAAR Study Data in Fabry Disease

                            Details : ST-920 (isaralgagene civaparvovec) is a liver-tropic rAAV 2/6 vector carrying the cDNA for human α-Gal A. It is being evaluated in phase 1/2 clinical trials for the treatment of Fabry Disease.

                            Product Name : ST-920

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            May 02, 2024

                            Lead Product(s) : Isaralgagene Civaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Sangamo Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Barclays

                            Deal Size : $24.0 million

                            Deal Type : Public Offering

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                            Sangamo Therapeutics Announces Pricing of $24.0 Million Registered Direct Offering

                            Details : Sangamo anticipates using net proceeds to fund the development of its neurology-focused genomic medicines pipeline, targeting the SCN9A gene for peripheral neuropathic pain.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 22, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Barclays

                            Deal Size : $24.0 million

                            Deal Type : Public Offering

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                            10

                            Sangamo Therapeutics

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                            Pharma Live Expo
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                            Sangamo Therapeutics

                            U.S.A arrow
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                            Not Confirmed
                            • fda
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                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : STAC-BBB

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Sangamo Announces Data on AAV Capsid Showing Blood-Brain Barrier Penetration

                            Details : STAC-BBB is a proprietary neurotropic AAV capsid showing blood-brain barrier penetration in preclinical studies, evaluated for treating prion disease and tauopathy.

                            Product Name : STAC-BBB

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            March 13, 2024

                            Lead Product(s) : STAC-BBB

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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