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Therapeutics","amount2":11.380000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Sarepta Therapeutics \/ Sarepta Therapeutics","highestDevelopmentStatusID":"12","companyTruncated":"Sarepta Therapeutics \/ Sarepta Therapeutics"}]

Find Clinical Drug Pipeline Developments & Deals by Sarepta Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the license agreement, Sarepta will gain exclusive global rights to several clinical and preclinical programs, including ARO-DUX4, which is being developed as a treatment for FSHD.

                          Brand Name : ARO-DUX4

                          Molecule Type : Large molecule

                          Upfront Cash : $825.0 million

                          November 26, 2024

                          Lead Product(s) : ARO-DUX4

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Arrowhead Pharmaceuticals

                          Deal Size : $11,375.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Elevidys (delandistrogene moxeparvovec) is a single-dose gene transfer therapy designed to address the underlying cause of DMD through the targeted production of micro-dystrophin in skeletal muscle.

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 20, 2024

                          Lead Product(s) : Delandistrogene Moxeparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Elevidys (delandistrogene moxeparvovec) is a single-dose, AAV based gene transfer therapy for intravenous infusion designed to address the underlying genetic cause of Duchenne muscular dystrophy.

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 20, 2024

                          Lead Product(s) : Delandistrogene Moxeparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Elevidys (delandistrogene moxeparvovec) is a single-dose, adeno-associated virus-based gene transfer therapy being evaluated for Duchenne muscular dystrophy with DMD gene mutation.

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 16, 2024

                          Lead Product(s) : Delandistrogene Moxeparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : SRP-5051 (vesleteplirsen) is a next-gen exon-skipping therapy in Phase 2 for Duchenne muscular dystrophy patients amenable to exon 51 skipping.

                          Brand Name : SRP-5051

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 29, 2024

                          Lead Product(s) : Vesleteplirsen

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : SRP-9003 (bidridistrogene xeboparvovec) is an investigational gene therapy that uses the AAVrh74 vector. Being evaluated in phase 3 clinical studies for limb-girdle muscular dystrophy type 2E/R4.

                          Brand Name : SRP-9003

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 16, 2024

                          Lead Product(s) : Bidridistrogene Xeboparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Elevidys (delandistrogene moxeparvovec-rokl) is a single-dose, adeno-associated virus (AAV) based gene transfer therapy for intravenous infusion designed to address the underlying genetic cause of Duchenne muscular dystrophy

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 22, 2023

                          Lead Product(s) : Delandistrogene Moxeparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Elevidys (delandistrogene moxeparvovec) is a single-dose gene transfer therapy for intravenous infusion designed to address the underlying cause of Duchenne muscular dystrophy through the targeted production of ELEVIDYS micro-dystrophin in skeletal muscl...

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 30, 2023

                          Lead Product(s) : Delandistrogene Moxeparvovec

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : In connection with this investment, the companies will explore the development of novel gene therapy candidates, including LX2021 and LX2022 for a range of cardiovascular diseases.

                          Brand Name : LX2021

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 28, 2023

                          Lead Product(s) : LX2021

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Discovery

                          Recipient : Lexeo Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Sarepta was awarded the PRV following U.S. FDA accelerated approval of ELEVIDYS (delandistrogene moxeparvovec-rokl) for the treatment of ambulatory pediatric patients aged 4 through 5 years with Duchenne muscular dystrophy with a confirmed mutation in th...

                          Brand Name : Elevidys

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 05, 2023

                          Lead Product(s) : Delandistrogene Moxeparvovec-rokl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Undisclosed

                          Deal Size : $102.0 million

                          Deal Type : Divestment

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