Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Hercules Capital
Deal Size : Undisclosed
Deal Type : Financing
Savara Enters Into Non-Dilutive Debt Financing for up to $200M with Hercules Capital
Details : The financing aims to fund the advance the clinical development of company's lead product Molbreevi (molgramostim). It is being evaluated for autoimmune pulmonary alveolar proteinosis.
Product Name : Molbreevi
Product Type : Protein
Upfront Cash : Undisclosed
March 26, 2025
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Hercules Capital
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Savara Submits BLA to FDA for MOLBREEVI for aPAP Treatment
Details : Molbreevi (molgramostim) is a GM-CSF agonist protein candidate. It is being evaluated for the treatment of autoimmune pulmonary alveolar proteinosis.
Product Name : Molbreevi
Product Type : Protein
Upfront Cash : Inapplicable
March 26, 2025
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Savara Initiates BLA Submission for MOLBREEVI in Autoimmune Pulmonary Alveolar Proteinosis
Details : Molbreevi (molgramostim) is a CSF-2R stimulant, drug candidate, which is being evaluated for autoimmune pulmonary alveolar proteinosis.
Product Name : Molbreevi
Product Type : Protein
Upfront Cash : Inapplicable
December 18, 2024
Lead Product(s) : Molgramostim
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Savara Launches Expanded Access Program For Molgramostim in aPAP Patients
Details : Molgramostim is an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis.
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Inapplicable
September 27, 2024
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $100.0 million
Deal Type : Public Offering
Savara Announces Pricing of $100.0 Million Underwritten Offering of Common Stock
Details : The net proceeds will be used to fund the clinical development and approval of molgramostim, which is being evaluated in the treatment of autoimmune pulmonary alveolar proteinosis.
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Undisclosed
June 28, 2024
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $100.0 million
Deal Type : Public Offering
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Savara Reports Molgramostim Achieved Significance in Phase 3 IMPALA-2 Trial for aPAP
Details : Molgramostim is an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis.
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Inapplicable
June 26, 2024
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $80.0 million
Deal Type : Public Offering
Details : The net proceeds will be used for the development of molgramostim nebulizer solution, an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP).
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Undisclosed
July 13, 2023
Lead Product(s) : Molgramostim
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $80.0 million
Deal Type : Public Offering
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Molgramostim is delivered via an investigational eFlow® Nebulizer System. Molgramostim nebulizer solution, is an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP...
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Inapplicable
June 26, 2023
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Molgramostim is delivered via an investigational eFlow® Nebulizer System. Molgramostim nebulizer solution, is an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP...
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Inapplicable
June 20, 2022
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Savara Presented Data at the European Respiratory Society (ERS) International Congress 2022
Details : Data demonstrated that patients treated with molgramostim after undergoing WLL had greater improvements in endpoint measures of gas exchange, including alveolar-arterial oxygen difference and diffusing capacity of the lungs for carbon monoxide corrected ...
Product Name : Molgradex
Product Type : Protein
Upfront Cash : Inapplicable
June 09, 2022
Lead Product(s) : Molgramostim
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable