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II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Hutchmed \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Hutchmed \/ Not Applicable"},{"orgOrder":0,"company":"Hutchmed","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Savolitinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Hutchmed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Hutchmed \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Hutchmed \/ Not Applicable"},{"orgOrder":0,"company":"Hutchmed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"HONG KONG","productType":"Other Small 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01

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orpathys (savolitinib) is an oral, potent and highly selective MET tyrosine kinase inhibitor. It is approved for MET exon 14 skipping altered NSCLC.

Product Name : Orpathys

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 13, 2025

Lead Product(s) : Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orpathys is an MET tyrosine kinase inhibitor. Tagrisso is a third-generation, irreversible EGFR TKI. These are being evaluated in combination with EGFR mutation-positive non-small cell lung cancer.

Product Name : Orpathys

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 01, 2025

Lead Product(s) : Savolitinib,Osimertinib Mesylate

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orpathys (savolitinib) is an oral, potent and highly selective MET tyrosine kinase inhibitor. It is investigated in combination with osimertinib for EGFR-mutated NSCLC.

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

December 11, 2024

Lead Product(s) : Savolitinib,Osimertinib Mesylate

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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04

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Tagrisso (osimertinib) is being evaluated in the mid-stage clinical trial studies in combination with Orpathys (savolitinib) for EFGR-mutated non-small cell lung cancer.

Product Name : Tagrisso

Product Type : Small molecule

Upfront Cash : Not Applicable

October 16, 2024

Lead Product(s) : Osimertinib Mesylate,Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orpathys (savolitinib) is an oral, potent and highly selective MET tyrosine kinase inhibitor. It is indicated for patients with non-small cell lung cancer with MET exon 14 skipping alterations.

Product Name : Orpathys

Product Type : Small molecule

Upfront Cash : Not Applicable

March 27, 2024

Lead Product(s) : Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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06

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orpathys (savolitinib), is an oral, potent and highly selective MET tyrosine kinase inhibitor that has demonstrated clinical activity in advanced solid tumors.

Product Name : Orpathys

Product Type : Small molecule

Upfront Cash : Not Applicable

August 28, 2023

Lead Product(s) : Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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07

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : ORPATHYS® (savolitinib), an oral, potent and highly selective MET tyrosine kinase inhibitor, has been included in the updated National Reimbursement Drug List for the treatment of locally advanced or metastatic NSCLC adult patients with MET exon 14-skip...

Product Name : Orpathys

Product Type : Small molecule

Upfront Cash : Undisclosed

January 18, 2023

Lead Product(s) : Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Approved

Sponsor : National Healthcare Security Administration

Deal Size : Undisclosed

Deal Type : Agreement

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08

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Preliminary results from SAVANNAH Phase II trial showed that TAGRISSO® (osimertinib) plus savolitinib demonstrated an ORR of 49% in patients with epidermal growth factor receptor-mutated NSCLC with high levels of mesenchymal epithelial transition overex...

Product Name : Tagrisso

Product Type : Small molecule

Upfront Cash : Not Applicable

August 08, 2022

Lead Product(s) : Osimertinib Mesylate,Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : AstraZeneca

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : The results from SAVANNAH suggest savolitinib added to Tagrisso (osimertinib) at the time of disease progression could possibly provide these biomarker-selected patients with a potentially less toxic, more effective treatment option.

Product Name : Tagrisso

Product Type : Small molecule

Upfront Cash : Not Applicable

August 08, 2022

Lead Product(s) : Osimertinib Mesylate,Savolitinib

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Hutchmed

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Savolitinib (ORPATHYS), is an oral, potent, and highly selective MET TKI that has demonstrated clinical activity in advanced solid tumors, blocks atypical activation of MET receptor tyrosine kinase pathway.

Product Name : Orpathys

Product Type : Small molecule

Upfront Cash : Not Applicable

July 13, 2022

Lead Product(s) : Savolitinib,Osimertinib Mesylate

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : AstraZeneca

Deal Size : Not Applicable

Deal Type : Not Applicable

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