Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Schrödinger Presents SGR-1505, a MALT1 Inhibitor, at ACS National Meeting
Details : SGR-1505 is a mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitor, small molecule drug candidate. It is being evaluated for relapsed/refractory B-cell malignancies.
Brand Name : SGR-1505
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 20, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery
Recipient : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Otsuka and Schrödinger Announce Single-Target, Drug Discovery Collaboration in Neurology
Details : Under the terms of the agreement, Schrödinger will be responsible for drug design through lead optimization and Otsuka will be responsible for all other drug discovery and clinical development activities, with the aim of rapidly expanding Otsuka's R&D p...
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
January 10, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery
Recipient : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : SGR-2921,Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The data presented demonstrate that SGR-2921 exhibits strong anti-tumor activity in vivo across multiple acute myeloid leukemia (AML) models, including cell-derived xenograft models, as a monotherapy and in combination with standard of care agents.
Brand Name : SGR-2921
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 12, 2022
Lead Product(s) : SGR-2921,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SGR-2921,Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Schrödinger is advancing SGR-2921 through investigational new drug (IND)-enabling studies with plans to initiate a Phase 1 trial in patients with relapsed/refractory acute myeloid leukemia (AML) in the second half of 2023.
Brand Name : SGR-2921
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 03, 2022
Lead Product(s) : SGR-2921,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery
Sponsor : Eli Lilly
Deal Size : $425.0 million
Deal Type : Collaboration
Schrödinger Hosts Platform Day
Details : Under the terms of the agreement, Schrödinger will be responsible for the discovery and optimization of small molecule compounds addressing the target. Lilly will be responsible for the completion of preclinical development, clinical development and com...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 06, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery
Sponsor : Eli Lilly
Deal Size : $425.0 million
Deal Type : Collaboration
Lead Product(s) : SGR-1505
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SGR-1505 is a mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitor that was discovered using Schrödinger’s proprietary physics-based computational platform.
Brand Name : SGR-1505
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 28, 2022
Lead Product(s) : SGR-1505
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Schrodinger has identified, highly selective Wee1 inhibitors with optimized physicochemical properties show strong pharmacodynamic responses and anti-tumor activity in preclinical models also increased DNA damage and mitosis in tumor cells leading to tum...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : Nimbus Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Nimbus Therapeutics and Schrödinger Collaborate to Discover Novel Therapeutics
Details : The collaboration has generated numerous promising therapeutic candidates, including small molecule inhibitors of acetyl-CoA carboxylase and TYK2, which are now in the clinic, and a MAP4K1/HPK1 inhibitor, which Nimbus plans to advance to the clinic later...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 12, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Nimbus Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Schrödinger and Zai Lab Announce a Global R&D Collaboration in Oncology
Details : The agreement provides Schrödinger with pipeline expansion opportunities in precision oncology and co-development and co-commercialization rights in the U.S.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
August 04, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : Bristol Myers Squibb
Deal Size : $2,755.0 million
Deal Type : Collaboration
Details : The collaboration combines Schrödinger’s physics-based computational platform and drug discovery capabilities with BMS's expertise in development and commercialization to advance small molecule therapeutics for targets in oncology, immunology, and neu...
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : $55.0 million
November 23, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : Bristol Myers Squibb
Deal Size : $2,755.0 million
Deal Type : Collaboration
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