Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Scribe Therapeutics Expands In Vivo Collaboration with Sanofi to Second Target
Details : Under the collaboration, Sanofi has exercised its option for a second target as part of the companies' research collaboration to develop CRISPR-based therapeutics using Scribe’s CRISPR technologies.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $40.0 million
January 03, 2024
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : Ex-vivo NK Cell Therapy
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Details : Under the collaboration, Sanofi receives an exclusive license to use Scribe’s CRISPR X-Editing (XE) genome editing technologies for the development of in vivo NK-cell therapies, including sickle cell disease.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $40.0 million
July 17, 2023
Lead Product(s) : Ex-vivo NK Cell Therapy
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : CRISPR-based Genetic Medicine
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Prevail Therapeutics
Deal Size : $1,575.0 million
Deal Type : Collaboration
Details : Under the collaboration, Prevail gets exclusive rights to Scribe’s CRISPR X-Editing (XE) technologies for the development of in vivo therapies directed to specified genetic targets known to cause serious neurological and neuromuscular diseases.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $75.0 million
May 16, 2023
Lead Product(s) : CRISPR-based Genetic Medicine
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Prevail Therapeutics
Deal Size : $1,575.0 million
Deal Type : Collaboration
Details : The agreement grants Sanofi non-exclusive rights to Scribe’s proprietary CRISPR platform of wholly owned enzymes to create ex vivo NK cell therapies for multiple oncology targets.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $25.0 million
September 27, 2022
Lead Product(s) : CRISPR-based Therapeutic
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : Biogen
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Scribe Therapeutics Expands Collaboration With Biogen to Second Target
Details : The expanded collaboration further validates Scribe’s position as a leading organization driving the development of novel CRISPR-based therapeutics that treat the underlying cause of disease.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 02, 2022
Lead Product(s) : CRISPR-based Therapeutic
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : Biogen
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Scribe Therapeutics Raises $100M Series B Financing to Further Develop “CRISPR by Design” Platform
Details : The capital will be used to further develop Scribe’s suite of custom gene editing and delivery technologies, as well as to advance a pipeline of therapeutics for neurodegeneration and additional diseases with high unmet need.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 31, 2021
Lead Product(s) : CRISPR based gene therapy
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : Biogen
Deal Size : $415.0 million
Deal Type : Collaboration
Details : Under the terms of the collaboration, Scribe will work with Biogen to create therapeutics for genetically-driven ALS, with an option to pursue an additional neurological disease target with high, unmet need.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $15.0 million
October 06, 2020
Lead Product(s) : CRISPR based gene therapy
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : Biogen
Deal Size : $415.0 million
Deal Type : Collaboration
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