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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : The SEED-Eisai Research Collaboration leverages Eisai’s expertise to advance the SEED early-stage product RBM39 for treating neurodegeneration and cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $1,500.0 million

                          August 06, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Eisai

                          Deal Size : $1,500.0 million

                          Deal Type : Collaboration

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                          02

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Lead Product(s) : ST-00937

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : ST-00937, a new chemical entity (NCE) molecular glue that has already achieved IND Candidate status and will be advanced for the treatment of cancers in SEED’s first IND filing, as early as 2024.

                          Product Name : ST-00937

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 26, 2023

                          Lead Product(s) : ST-00937

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : The collaboration aims to discover and develop new chemical entities (NCEs) that could produce therapeutic benefit through targeted protein degradation (TPD).

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : $10.0 million

                          November 13, 2020

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Eli Lilly

                          Deal Size : $800.0 million

                          Deal Type : Collaboration

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