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Biotherapeutics","sponsor":"Citigroup","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2021","type":"Public Offering","leadProduct":"Pembrolizumab","moa":"Aspartyl beta hydroxylase","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Sensei Biotherapeutics","amount2":0.13,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.13,"dosageForm":"injection","sponsorNew":"Sensei Biotherapeutics \/ Citigroup","highestDevelopmentStatusID":"7","companyTruncated":"Sensei Biotherapeutics \/ Citigroup"},{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"SNS-101","moa":"VISTA checkpoint","graph1":"Oncology","graph2":"Phase I","graph3":"Sensei Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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molecule","year":"2022","type":"Not Applicable","leadProduct":"SNS-101","moa":"VISTA checkpoint","graph1":"Oncology","graph2":"Phase I","graph3":"Sensei Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sensei Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Sensei Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"SNS-102","moa":"PSGL-1","graph1":"Oncology","graph2":"Preclinical","graph3":"Sensei Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sensei Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Sensei Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Washington University","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"SNS-101","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Sensei Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Sensei Biotherapeutics \/ Washington University","highestDevelopmentStatusID":"4","companyTruncated":"Sensei Biotherapeutics \/ Washington University"},{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not 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Find Clinical Drug Pipeline Developments & Deals by Sensei Biotherapeutics

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody, designed to selectively block the immune checkpoint VISTA in the tumor microenvironment, which acts as a suppressor of T cells by binding the receptor PSGL-1.

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 27, 2023

                          Lead Product(s) : SNS-101,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody, designed to selectively block the immune checkpoint VISTA in the tumor microenvironment, which acts as a suppressor of T cells by binding the receptor PSGL-1.

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 01, 2023

                          Lead Product(s) : SNS-101,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 20, 2023

                          Lead Product(s) : SNS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 21, 2023

                          Lead Product(s) : SNS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-103 is a conditionally active, monoclonal antibody targeting ENTPDase1 (CD39), an enzyme commonly upregulated by tumors and involved in the conversion of ATP into immunosuppressive adenosine in the tumor microenvironment.

                          Brand Name : SNS-103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 14, 2023

                          Lead Product(s) : SNS-103

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 14, 2023

                          Lead Product(s) : SNS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the terms of the CRADA, Sensei will collaborate with the NCI to expand the development of SNS-101, a conditionally active, pH-selective VISTA-blocking antibody and to assess the mechanism of action of SNS-101 in combination with novel therapeutic m...

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          February 06, 2023

                          Lead Product(s) : SNS-101,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : National Institutes of Health

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The supply agreement supports the evaluation of SNS-101, a conditionally active VISTA-blocking antibody, in combination with Libtayo® in a Phase 1/2 trial in solid tumors.

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 05, 2023

                          Lead Product(s) : SNS-101,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Regeneron Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101, a conditionally active antibody targeting the immune checkpoint VISTA, as well as its other TMAb™ (Tumor Microenvironment Activated biologics) platform programs.

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 08, 2022

                          Lead Product(s) : SNS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SNS-101 has the potential to unlock VISTA as a powerful immune checkpoint by exploiting the tumor microenvironment using pH-sensitive properties, delivering powerful anti-tumor activity without the negative effects that have thwarted past efforts.

                          Brand Name : SNS-101

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 21, 2022

                          Lead Product(s) : SNS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Washington University

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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