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    [{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Sensei Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Acquisition","leadProduct":"Nanobodies","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Sensei Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sensei Biotherapeutics \/ Sensei Biotherapeutics","highestDevelopmentStatusID":"2","companyTruncated":"Sensei Biotherapeutics \/ Sensei Biotherapeutics"},{"orgOrder":0,"company":"Sensei Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Pembrolizumab","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Sensei 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                            01

                            Sensei Biotherapeutics

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                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Announces Initiation of Combination Arm for Phase 1/2 Clinical Study of SNS-101 with Re...

                            Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody, designed to selectively block the immune checkpoint VISTA in the tumor microenvironment, which acts as a suppressor of T cells by binding the receptor PSGL-1.

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 27, 2023

                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Announces First Patient Dosed in Phase 1/2 Clinical Trial of SNS-101, a Conditionally A...

                            Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody, designed to selectively block the immune checkpoint VISTA in the tumor microenvironment, which acts as a suppressor of T cells by binding the receptor PSGL-1.

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 01, 2023

                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Announces IND Clearance by U.S. FDA Enabling Phase 1 Initiation for SNS-101, a Conditio...

                            Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 20, 2023

                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Announces Submission of Investigational New Drug (IND) Application for SNS-101, a Condi...

                            Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 21, 2023

                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Sensei Biotherapeutics

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                            Lead Product(s) : SNS-103

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics to Present New Preclinical Data for SNS-103, a Conditionally Active Monoclonal Antibody...

                            Details : SNS-103 is a conditionally active, monoclonal antibody targeting ENTPDase1 (CD39), an enzyme commonly upregulated by tumors and involved in the conversion of ATP into immunosuppressive adenosine in the tumor microenvironment.

                            Brand Name : SNS-103

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 14, 2023

                            Lead Product(s) : SNS-103

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Sensei Biotherapeutics

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                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics to Present New Preclinical Data for SNS-101, a Conditionally Active VISTA-blocking Anti...

                            Details : SNS-101 is a conditionally active, human monoclonal IgG1 antibody designed to block the VISTA checkpoint, which acts as a suppressor of T cells by binding the receptor PSGL-1. SNS-101 addresses the problems by binding only in the low-pH tumor microenviro...

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 14, 2023

                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Sensei Biotherapeutics

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                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Signs Cooperative Research and Development Agreement (CRADA) with the National Cancer I...

                            Details : Under the terms of the CRADA, Sensei will collaborate with the NCI to expand the development of SNS-101, a conditionally active, pH-selective VISTA-blocking antibody and to assess the mechanism of action of SNS-101 in combination with novel therapeutic m...

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 06, 2023

                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Regeneron Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Announces Clinical Supply Agreement with Regeneron for Phase 1/2 Clinical Trial Evaluat...

                            Details : The supply agreement supports the evaluation of SNS-101, a conditionally active VISTA-blocking antibody, in combination with Libtayo® in a Phase 1/2 trial in solid tumors.

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 05, 2023

                            Lead Product(s) : SNS-101,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Regeneron Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sensei Biotherapeutics Provides Update on Strategic Priorities

                            Details : SNS-101, a conditionally active antibody targeting the immune checkpoint VISTA, as well as its other TMAb™ (Tumor Microenvironment Activated biologics) platform programs.

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 08, 2022

                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Sensei Biotherapeutics

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                            Sensei Biotherapeutics

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                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Washington University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Sensei Biotherapeutics Announces Collaboration with Washington University, St. Louis to Support Development of...

                            Details : SNS-101 has the potential to unlock VISTA as a powerful immune checkpoint by exploiting the tumor microenvironment using pH-sensitive properties, delivering powerful anti-tumor activity without the negative effects that have thwarted past efforts.

                            Brand Name : SNS-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 21, 2022

                            Lead Product(s) : SNS-101

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Washington University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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