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Find Clinical Drug Pipeline Developments & Deals by Senti Biosciences

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The Company intends to use the net proceeds from the offering to fund the continued development of its SENTI-202 program for treating acute myeloid leukemia.

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 06, 2025

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Celadon Partners

                          Deal Size : $47.6 million

                          Deal Type : Financing

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                          02

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The net proceeds will be used to fund the clinical development of the company's lead product SENTI-202, which is being evaluated for the treatment of acute myeloid leukemia & Hematologic Malignancies

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 02, 2024

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Celadon Partners

                          Deal Size : $37.6 million

                          Deal Type : Private Placement

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                          03

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : SENTI-202 is a potential first-in-class off-the-shelf CAR-NK cell therapy which selectively target cancer cells while sparing healthy bone marrow cells. It is being evaluated for the treatment of AML.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 02, 2024

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The CIRM grant will support the ongoing clinical development of SENTI-202, which is being evaluated in early-stage clinical trial studies for treating acute myeloid leukemia.

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 05, 2024

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : California Institute for Regenerative Medicines

                          Deal Size : $8.0 million

                          Deal Type : Funding

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                          05

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The proceeds will advance the development of SENTI-202, a potential first-in-class Logic Gated off-the-shelf CAR-NK cell therapy, for relapsed/refractory hematologic malignancies including AML.

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 01, 2024

                          Lead Product(s) : SENTI-202,Cytarabine,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : California Institute for Regenerative Medicines

                          Deal Size : $8.0 million

                          Deal Type : Funding

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                          06

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : SENTI-202 is a Logic Gated off-the-shelf CAR-NK cell therapy designed to selectively target and eliminate CD33 and/or FLT3 expressing hematologic malignancies, such as acute myeloid leukemia.

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 13, 2024

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : SENTI-202 is an off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cell therapy product candidate designed to selectively target and eliminate CD33 and/or FLT3 expressing hematologic malignancies including acute myeloid leukemia.

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 22, 2023

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : SENTI-202 is a potential first-in-class off-the-shelf CAR-NK cell therapy using Logic Gated Gene Circuits to selectively target cancer cells while sparing healthy bone marrow cells. It is being evaluated for the treatment of acute myeloid leukemia (AML).

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 05, 2023

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Under the collaboration, Celest will lead clinical development for the advancement of SENTI-301A, a multi-armed off-the-shelf healthy donor derived CAR-NK cell therapy designed for the treatment of GPC3 expressing tumors.

                          Product Name : SENTI-301A

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 06, 2023

                          Lead Product(s) : SENTI-301A

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Celest Therapeutics

                          Deal Size : $156.0 million

                          Deal Type : Collaboration

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                          10

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Under the partnership, GeneFab will support manufacturing of Senti’s chimeric antigen receptor natural killer (CAR-NK) medicines pipeline, including SENTI-202, for the treatment of CD33 and/or FLT3 expressing hematologic malignancies, such as AML and M...

                          Product Name : SENTI-202

                          Product Type : Cell and Gene therapy

                          Upfront Cash : $38.0 million

                          August 10, 2023

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : GeneFab

                          Deal Size : $38.0 million

                          Deal Type : Acquisition

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