[{"orgOrder":0,"company":"Septerna","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Series B Financing","leadProduct":"Undisclosed","moa":"","graph1":"Endocrinology","graph2":"Preclinical","graph3":"Septerna","amount2":0.14999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0.14999999999999999,"dosageForm":"","sponsorNew":"Septerna \/ RA Capital Management","highestDevelopmentStatusID":"4","companyTruncated":"Septerna \/ RA Capital Management"},{"orgOrder":0,"company":"Septerna","sponsor":"Vertex Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Technology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Acquisition","leadProduct":"Undisclosed","moa":"","graph1":"Technology","graph2":"Discovery Platform","graph3":"Septerna","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Technology","amount2New":0,"dosageForm":"","sponsorNew":"Septerna \/ Vertex Pharmaceuticals","highestDevelopmentStatusID":"3","companyTruncated":"Septerna \/ Vertex Pharmaceuticals"},{"orgOrder":0,"company":"Septerna","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"SEP-786","moa":"","graph1":"Endocrinology","graph2":"Phase I","graph3":"Septerna","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"Septerna \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Septerna \/ Not Applicable"},{"orgOrder":0,"company":"Septerna","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"SEP-786","moa":"","graph1":"Endocrinology","graph2":"Phase I","graph3":"Septerna","amount2":0.28999999999999998,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0.33000000000000002,"dosageForm":"","sponsorNew":"Septerna \/ J.P. Morgan","highestDevelopmentStatusID":"6","companyTruncated":"Septerna \/ J.P. Morgan"},{"orgOrder":0,"company":"Septerna","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"SEP-786","moa":"","graph1":"Endocrinology","graph2":"Phase I","graph3":"Septerna","amount2":0.33000000000000002,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0.33000000000000002,"dosageForm":"","sponsorNew":"Septerna \/ J.P. Morgan","highestDevelopmentStatusID":"6","companyTruncated":"Septerna \/ J.P. Morgan"},{"orgOrder":0,"company":"Septerna","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"SEP-786","moa":"","graph1":"Endocrinology","graph2":"Phase I","graph3":"Septerna","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0.33000000000000002,"dosageForm":"","sponsorNew":"Septerna \/ J.P. Morgan","highestDevelopmentStatusID":"6","companyTruncated":"Septerna \/ J.P. Morgan"}]

Find Clinical Drug Pipeline Developments & Deals by Septerna

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                          Top Deals by Deal Size (USD bn)

                          01

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.

                          Brand Name : SEP-786

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 30, 2024

                          Lead Product(s) : SEP-786

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : J.P. Morgan

                          Deal Size : $331.2 million

                          Deal Type : Public Offering

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                          02

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.

                          Brand Name : SEP-786

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 24, 2024

                          Lead Product(s) : SEP-786

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : J.P. Morgan

                          Deal Size : $288.0 million

                          Deal Type : Public Offering

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                          03

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.

                          Brand Name : SEP-786

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 03, 2024

                          Lead Product(s) : SEP-786

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : J.P. Morgan

                          Deal Size : Undisclosed

                          Deal Type : Public Offering

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                          04

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : SEP-786 is a novel, potent, and selective, oral small molecule parathyroid hormone 1 receptor (PTH1R) agonist. It is being developed for the treatment of patients with hypoparathyroidism.

                          Brand Name : SEP-786

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 27, 2024

                          Lead Product(s) : SEP-786

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : Under the terms of the acquisition, Vertex will be responsible for continuing the research and development of the novel undisclosed discovery-stage GPCR program.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : $47.5 million

                          September 12, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Vertex Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          06

                          Cosmoprof
                          Not Confirmed
                          Cosmoprof
                          Not Confirmed

                          Details : The proceeds will fund the development of company's novel products targeting well-validated GPCRs, including advancement of its lead program targeting the parathyroid hormone 1 receptor, and preclinical advancement of its program targeting thyroid stimul...

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 11, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : RA Capital Management

                          Deal Size : $150.0 million

                          Deal Type : Series B Financing

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