Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Septerna Halts SEP-786 Phase 1, Focuses on Next-Gen PTH1R Agonist
Details : SEP-786 is an oral small molecule agonist of the parathyroid hormone 1 receptor (PTH1R). which is being developed for the treatment of hypoparathyroidism.
Product Name : SEP-786
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 18, 2025
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : J.P. Morgan
Deal Size : $331.2 million
Deal Type : Public Offering
Septerna Announces Closing of $331.2 Million Upsized Initial Public Offering
Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.
Product Name : SEP-786
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 30, 2024
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : J.P. Morgan
Deal Size : $331.2 million
Deal Type : Public Offering
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : J.P. Morgan
Deal Size : $288.0 million
Deal Type : Public Offering
Septerna Prices Upsized Initial Public Offering
Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.
Product Name : SEP-786
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 24, 2024
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : J.P. Morgan
Deal Size : $288.0 million
Deal Type : Public Offering
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Septerna Initiates Phase 1 Trial For SEP-786 to Treat Hypoparathyroidism
Details : SEP-786 is a novel, potent, and selective, oral small molecule parathyroid hormone 1 receptor (PTH1R) agonist. It is being developed for the treatment of patients with hypoparathyroidism.
Product Name : SEP-786
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 27, 2024
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
GPCR Firm Septerna Files for IPO on Strength of Preclinical Data
Details : The net proceeds will be used to fund the clinical development of company's lead product, SEP-786, which is being evaluated for the treatment of Hypoparathyroidism.
Product Name : SEP-786
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 10, 2024
Lead Product(s) : SEP-786
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Septerna Announces Novel GPCR-targeted Program Acquired by Vertex
Details : Under the terms of the acquisition, Vertex will be responsible for continuing the research and development of the novel undisclosed discovery-stage GPCR program.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $47.5 million
December 09, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : RA Capital Management
Deal Size : $150.0 million
Deal Type : Series B Financing
Details : The proceeds will fund the development of company's novel products targeting well-validated GPCRs, including advancement of its lead program targeting the parathyroid hormone 1 receptor, and preclinical advancement of its program targeting thyroid stimul...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 07, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : RA Capital Management
Deal Size : $150.0 million
Deal Type : Series B Financing