Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : XOMA
Deal Size : $20.0 million
Deal Type : Acquisition
XOMA Acquires Pulmokine for $20M Adding Seralutinib Phase 3 Royalty Interest
Details : Through the acquisition, XOMA add GB002 (seralutinib), a potent PDGFR, colony stimulating factor 1 receptor, and c-KIT kinase inhibitor, Phase 3 asset being studied in pulmonary arterial hypertension.
Product Name : 20
Product Type : Small molecule
Upfront Cash : $20.0 million
December 02, 2024
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : XOMA
Deal Size : $20.0 million
Deal Type : Acquisition
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Chiesi Group
Deal Size : $326.0 million
Deal Type : Collaboration
Gossamer Bio and Chiesi Group Collaborate to Develop Seralutinib for PAH and PH-ILD
Details : Gossamer Bio continues developing GB002 (seralutinib), an inhaled inhibitor for pulmonary hypertension, while Chiesi will commercialize it outside the U.S.
Product Name : GB002
Product Type : Small molecule
Upfront Cash : Undisclosed
May 06, 2024
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Chiesi Group
Deal Size : $326.0 million
Deal Type : Collaboration
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : New Enterprise Associates
Deal Size : $212.0 million
Deal Type : Private Placement
Gossamer Bio Announces $212 Million Private Placement Financing
Details : Gossamer intends to use the net proceeds to fund the ongoing development and commercialization of GB002 (seralutinib), a tyrosine kinase inhibitor targeting PDGFRα/β, CSF1R, and c-KIT, for the treatment of pulmonary arterial hypertension (PAH).
Product Name : GB002
Product Type : Small molecule
Upfront Cash : Undisclosed
July 20, 2023
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : New Enterprise Associates
Deal Size : $212.0 million
Deal Type : Private Placement
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Gossamer Bio Announces Seralutinib Meets Primary Endpoint in Phase 2 TORREY Study in PAH
Details : The efficacy results generated with GB002 (seralutinib) in the context of a favorable safety and tolerability profile highlight compelling potential differentiation for seralutinib as an anti-proliferative, anti-inflammatory, and anti-fibrotic therapeuti...
Product Name : GB002
Product Type : Small molecule
Upfront Cash : Not Applicable
December 06, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : EcoR1 Capital
Deal Size : $120.0 million
Deal Type : Private Placement
Gossamer Bio Announces $120 Million Private Placement Financing
Details : Gossamer intends to use the net proceeds from the proposed financing to fund research and development of its other product candidates and development programs and for working capital and general corporate purposes.
Product Name : GB002
Product Type : Small molecule
Upfront Cash : Undisclosed
July 13, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : EcoR1 Capital
Deal Size : $120.0 million
Deal Type : Private Placement
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. The primary objective for this trial is to determine the effect of GB002 on improving pulmonary hemodynamics in subjects with WHO Group 1 PAH who are Functional Class II and III.
Product Name : GB002
Product Type : Small molecule
Upfront Cash : Not Applicable
June 09, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable