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                          Top Deals by Deal Size (USD bn)

                          01

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : SER-155 decreases the colonization and abundance of bacterial pathogens, and to enhance epithelial barrier integrity in the GI tract, decreasing the incidence of bloodstream infections.

                          Product Name : SER-155

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : SER-155,Vancomycin Hydrochloride

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : SER-155 decreases the colonization and abundance of bacterial pathogens, and to enhance epithelial barrier integrity in the GI tract, decreasing the incidence of bloodstream infections.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 09, 2024

                          Lead Product(s) : SER-155,Vancomycin Hydrochloride

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : SER-155 decreases the colonization and abundance of bacterial pathogens, and to enhance epithelial barrier integrity in the GI tract, decreasing the incidence of bloodstream infections.

                          Product Name : SER-155

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 12, 2024

                          Lead Product(s) : SER-155,Vancomycin Hydrochloride

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : Seres Therapeutics has signed an agreement with Nestlé Health Science to sell its VOWST, an FDA-approved oral therapy for preventing recurrent Clostridioides difficile infections (CDI).

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : $250.0 million

                          August 06, 2024

                          Lead Product(s) : Fecal Microbiota Spores, Live

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Nestlé Health Science

                          Deal Size : $525.0 million

                          Deal Type : Agreement

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                          05

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : Nestlé will acquire certain assets associated with VOWST (fecal microbiota spores), the first and only FDA approved oral therapeutic to prevent recurrence of Clostridioides difficile infection.

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 06, 2024

                          Lead Product(s) : Fecal Microbiota Spores Live

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Nestle Health Sciences SA

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          06

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : Vowst (fecal microbiota spores, live-brpk) is approved by FDA as the first orally administered microbiota-based therapeutic for the prevention of recurrent C. difficile infection (CDI).

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 05, 2023

                          Lead Product(s) : Fecal Microbiota Spores Live-brpk

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Nestle Health Sciences SA

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : The agreement aimed to jointly commercialize Vowst (fecal microbiota spores, live-brpk), an orally administered microbiota-based therapeutic to prevent recurrence of C. difficile Infection in adults following antibiotic treatment for recurrent CDI, follo...

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : $175 million

                          May 30, 2023

                          Lead Product(s) : Fecal Microbiota Spores Live-brpk

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Nestle Health Sciences SA

                          Deal Size : $525 million

                          Deal Type : Agreement

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                          08

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : The financing will support the commercial launch of Vowst, the first orally administered microbiota-based therapeutic to prevent recurrence of C. difficile Infection in adults following antibacterial treatment for recurrent CDI and to fund company's pipe...

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 27, 2023

                          Lead Product(s) : Fecal Microbiota Spores Live-brpk

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Oaktree Capital Management

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          09

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : Vowst (fecal microbiota spores, live-brpk) is approved by FDA as the first orally administered microbiota-based therapeutic for the prevention of recurrent C. difficile infection (CDI).

                          Product Name : Vowst

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 26, 2023

                          Lead Product(s) : Fecal Microbiota Spores Live-brpk

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Nestle Health Sciences SA

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          euroPLX 87
                          Not Confirmed
                          euroPLX 87
                          Not Confirmed

                          Details : SER-109 is an oral microbiome therapeutic candidate consisting consortium of highly purified Firmicutes spores. It is designed to prevent further recurrences of CDI by modulating the disrupted microbiome to a state that resists C. difficile colonization ...

                          Product Name : SER-109

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 14, 2023

                          Lead Product(s) : Firmicute Species Bacterial Spores

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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