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    [{"orgOrder":0,"company":"Sesen Bio","sponsor":"Cardinal Health","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"Vicineum","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sesen Bio \/ Sesen Bio","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Sesen Bio"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Carisma Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Merger","leadProduct":"CT-0508","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sesen Bio \/ Sesen Bio","highestDevelopmentStatusID":"6","companyTruncated":"Sesen Bio \/ Sesen Bio"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Carisma Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Merger","leadProduct":"CT-0508","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Sesen Bio \/ Carisma Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Sesen Bio \/ Carisma Therapeutics"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Carisma Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2022","type":"Merger","leadProduct":"Oportuzumab Monatox","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Sesen Bio \/ Sesen Bio","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Sesen Bio"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Oportuzumab Monatox","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Liquid, Instillation","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Oportuzumab Monatox","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Liquid, Instillation","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Viventia Bio","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Oportuzumab Monatox","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Oportuzumab Monatox","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Liquid, Instillation","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Vicineum","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Qilu Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Agreement","leadProduct":"Vicineum","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Sesen Bio \/ Qilu Pharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Qilu Pharmaceutical"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Vicineum","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"},{"orgOrder":0,"company":"Sesen Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Vicineum","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase III","graph3":"Sesen Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Sesen Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sesen Bio \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Sesen Bio

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                            01

                            Sesen Bio

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                            The Generic Rx Session
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                            The Generic Rx Session
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                            Lead Product(s) : CT-0508,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Carisma Therapeutics Closes Merger with Sesen Bio

                            Details : The combined company will develop Carisma's lead candidate CT-0508, a CAR-M cell therapy and will also accelerate the growth of company's platform and pipeline within and outside of oncology.

                            Product Name : CT-0508

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 21, 2023

                            Lead Product(s) : CT-0508,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            02

                            Sesen Bio

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                            The Generic Rx Session
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                            Sesen Bio

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                            The Generic Rx Session
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Carisma Therapeutics

                            Deal Size : $30.0 million

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Sesen Bio and Carisma Therapeutics Announce Substantial Increase to Expected Special Cash Dividend in Connecti...

                            Details : Vicineum (oportuzumab monatox) is an investigational locally administered recombinant fusion protein that targets epithelial cell adhesion molecule antigens on the surface of tumor cells to deliver Pseudomonas Exotoxin A.

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Undisclosed

                            December 29, 2022

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Carisma Therapeutics

                            Deal Size : $30.0 million

                            Deal Type : Merger

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                            03

                            Sesen Bio

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                            The Generic Rx Session
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                            Sesen Bio

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                            The Generic Rx Session
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                            Lead Product(s) : CT-0508

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Sesen Bio and Carisma Therapeutics Announce Merger Agreement

                            Details : The first clinical application of this technology is CT-0508, a CAR-M cell therapy currently being evaluated by Carisma in a Phase 1 multi-center clinical trial with a lead target indication of advanced HER2+ solid tumors.

                            Product Name : CT-0508

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 21, 2022

                            Lead Product(s) : CT-0508

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            Sesen Bio

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                            The Generic Rx Session
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                            Sesen Bio

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                            The Generic Rx Session
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                            Lead Product(s) : Vicineum

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Announces Strategic Decision to Pause Clinical Development of Vicineumâ„¢ in the US

                            Details : VB4-845 (vicineum), a locally administered fusion protein for treatment of NMIBC, is comprised of a recombinant fusion protein that targets epithelial cell adhesion molecule antigens on surface of tumor cells to deliver a potent protein payload, Pseudomo...

                            Product Name : VB4-845

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            July 18, 2022

                            Lead Product(s) : Vicineum

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Sesen Bio

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                            The Generic Rx Session
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                            Sesen Bio

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Expands CMC and Clinical Teams

                            Details : Vicineum is comprised of a recombinant fusion protein that targets epithelial cell adhesion molecule (EpCAM) antigens on the surface of tumor cells to deliver a potent protein payload, Pseudomonas Exotoxin A.

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            October 12, 2021

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Sesen Bio

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                            The Generic Rx Session
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                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Receives Complete Response Letter from FDA for Vicineumâ„¢ (oportuzumab monatox-qqrs)

                            Details : Vicineum is comprised of a recombinant fusion protein that targets epithelial cell adhesion molecule (EpCAM) antigens on the surface of tumor cells to deliver a potent protein payload, Pseudomonas Exotoxin A.

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            August 13, 2021

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Approaches the Potential Approval and Commercial Launch of Vicineumâ„¢

                            Details : Vicineum is comprised of a recombinant fusion protein that targets EpCAM antigens on the surface of tumor cells to deliver a potent protein payload, Pseudomonas Exotoxin A. It is currently under Priority Review with the FDA with a target PDUFA date of Au...

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            August 11, 2021

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Strengthens Leadership Team as the Company Approaches the Potential Approval and Launch of Vicineumâ...

                            Details : Vicineum is constructed with a stable, genetically engineered peptide tether to ensure the payload remains attached to the antibody binding fragment until it is internalized by the cancer cell.

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            August 02, 2021

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Sesen Bio

                            U.S.A arrow
                            The Generic Rx Session
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                            Sesen Bio

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                            The Generic Rx Session
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                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Viventia Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Announces FDA Acceptance and Priority Review of its Biologics License Application for Vicineumâ„¢

                            Details : Vicineum, a locally administered fusion protein, is Sesen Bio’s lead product candidate being developed for the treatment of high-risk non-muscle invasive bladder cancer (NMIBC).

                            Product Name : Vicineum

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            February 16, 2021

                            Lead Product(s) : Oportuzumab Monatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Viventia Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Sesen Bio

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                            The Generic Rx Session
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                            The Generic Rx Session
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                            Lead Product(s) : Vicineum

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sesen Bio Submits Completed Biologics License Application to the FDA for Vicineumâ„¢ and Has Requested Priorit...

                            Details : Vicineum, a locally administered fusion protein, is Sesen Bio’s lead product candidate being developed for the treatment of high-risk non-muscle invasive bladder cancer (NMIBC). The BLA is supported by strong Phase 3 VISTA trial data and positive analy...

                            Product Name : VB4-845

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 21, 2020

                            Lead Product(s) : Vicineum

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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