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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Rhythm Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Rhythm Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Rhythm Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Peptide","year":"2024","type":"Not Applicable","leadProduct":"Setmelanotide Acetate","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Rhythm Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Rhythm Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Rhythm Pharmaceuticals \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for Setmelanotide Acetate

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          August 26, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          July 31, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the 1st & only therapy approved in Canada for weight management in adult & pediatric patients (≥6 years) with obesity due to Bardet-Biedl syndrome.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          June 28, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the 1st & only therapy approved in Canada for weight management in adult & pediatric patients (≥6 years) with obesity due to Bardet-Biedl syndrome.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          May 22, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The Company intends to use the proceeds to fund clinical programs, including IMCIVREE, an MC4R agonist for treating hyperphagia and severe obesity, approved for chronic weight management.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          April 01, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Perceptive Advisors LLC

                          Deal Size : $150.0 million

                          Deal Type : Financing

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 receptor agonist for chronic weight management in patients 6 years and older with monogenic or syndromic obesity, under evaluation for hypothalamic obesity.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          February 22, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide), an MC4R agonist for hyperphagia and severe obesity, is FDA-approved for chronic weight management and in phase 3 trials for hypothalamic obesity.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          January 04, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a melanocortin 4 (MC4) receptor agonist. It is the first and only therapy approved in Canada for weight management in adult and pediatric patients 6 years of age and older with obesity due to Bardet-Biedl syndrome (BBS).

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          November 02, 2023

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a melanocortin 4 (MC4) receptor agonist, which is investigated for the treatment of treatment for acquired hypothalamic obesity.

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          September 18, 2023

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the agreement, Genpharm will distribute Imcivree (setmelanotide) to patients in GCC countries for the treatment of hyperphagia and obesity due to Bardet-Biedl syndrome or genetically-confirmed biallelic pro-opiomelanocortin, PCSK1, or leptin recept...

                          Brand Name : Imcivree

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          May 22, 2023

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Approved

                          Sponsor : Genpharm

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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