Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Edgewise Receives EMA Orphan Drug Designation for Sevasemten in Muscular Dystrophies
Details : EDG-5506 (sevasemten) is an investigational orally administered small molecule, MYH4 inhibitor. It is being developed for the treatment of becker & duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 23, 2024
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Edgewise Announces Positive Two-Year Results from Sevasemten Trial
Details : EDG-5506 (sevasemten) is an orally administered small molecule designed to prevent contraction-induced muscle damage. Currently is being evaluated in clinical trials for Duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 15, 2024
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Edgewise Receives FDA Fast Track Designation for EDG-5506 in Duchenne Muscular Dystrophy
Details : EDG-5506 is an investigational orally administered small molecule, MYH4 inhibitor. It is being developed for the treatment of duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2024
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : RA Capital Management
Deal Size : $240.0 million
Deal Type : Public Offering
Edgewise Therapeutics Announces Pricing Of $240 Million Underwritten Offering
Details : Edgewise intends to use net proceeds to support the potential U.S. launch of EDG-5506 (sevasemten), an orally administered skeletal myosin inhibitor in patients with Becker muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 19, 2024
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : RA Capital Management
Deal Size : $240.0 million
Deal Type : Public Offering
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is a small molecule tablet which works by inhibiting Myosin ATPase, it is currently being investigated in adults for treating Becker Muscular Dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 30, 2023
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is an orally administered small molecule designed to prevent contraction-induced muscle damage in dystrophinopathies including Becker Muscular Dystrophy and Duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 26, 2023
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is an orally administered small molecule designed to prevent contraction-induced muscle damage in dystrophinopathies including Becker Muscular Dystrophy and Duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 26, 2023
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Medpace, Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is an orally administered small molecule designed to prevent contraction-induced muscle damage in dystrophinopathies including Becker Muscular Dystrophy and Duchenne muscular dystrophy.
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 26, 2023
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Medpace, Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is an investigational orally administered small molecule myosin modulator designed to protect injury-susceptible fast skeletal muscle fibers in dystrophinopathies such as DMD and Becker muscular dystrophy (BMD).
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 27, 2022
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EDG-5506 is an orally administered small molecule designed to address muscle damage induced by mechanical stress in dystrophinopathies including Becker and Duchenne Muscular Dystrophy (DMD and BMD).
Brand Name : EDG-5506
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2022
Lead Product(s) : Sevasemten
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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