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Find Clinical Drug Pipeline Developments & Deals by SFJ Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Through the acquisition, SERB has acquired exclusive US rights to the ticagrelor reversal agent PB2452 (bentracimab), a novel, monoclonal antibody fragment, from SFJ. SFJ will remain responsible for the ongoing trials of bentracimab and will work with SE...

                          Brand Name : PB2452

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          May 11, 2023

                          Lead Product(s) : Bentracimab

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase III

                          Sponsor : Serb

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : PB2452 (bentracimab) is a novel, recombinant, human monoclonal antibody antigen-binding fragment designed to reverse the antiplatelet activity of ticagrelor in major bleeding and urgent surgery situations.

                          Brand Name : PB2452

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 17, 2023

                          Lead Product(s) : Bentracimab

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase III

                          Recipient : PhaseBio Pharmaceuticals

                          Deal Size : $120.0 million

                          Deal Type : Collaboration

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : In the study, EMPAVELI met the primary endpoint, demonstrating superiority to Soliris for the change from baseline in hemoglobin level at Week 16 with an adjusted mean increase of 3.84 g/dL of hemoglobin.

                          Brand Name : Empaveli

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          May 14, 2021

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase IV

                          Recipient : Apellis Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The collaboration between SFJ and Nektar will support a new Phase 2/3 registrational clinical study of BEMPEG plus pembrolizumab in patients with head and neck cancer whose tumors express PD-L1 (Combined Positive Score).

                          Brand Name : NKTR-214

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          February 17, 2021

                          Lead Product(s) : Bempegaldesleukin,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Nektar Therapeutics

                          Deal Size : $150.0 million

                          Deal Type : Collaboration

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The collaboration with SFJ provides PhaseBio with substantial funding to continue the rapid advancement of lead program, PB2452.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 10, 2020

                          Lead Product(s) : PB2452

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Recipient : PhaseBio Pharmaceuticals

                          Deal Size : $120.0 million

                          Deal Type : Collaboration

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