Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SQL70,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Johnson & Johnson
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Shasqi to Expand Existing Research Collaboration to Advance Targeted Cancer Treatment
Details : Through the collaboration, Shasqi will apply its novel tumor-targeted Click Activated Protodrugs Against Cancer (CAPAC®) platform to the development of new cancer therapies and research on Shasqi's intratumorally injected biopolymer, SQ3370 (SQL70).
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 04, 2023
Lead Product(s) : SQL70,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Johnson & Johnson
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Lead Product(s) : SQL70,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Johnson & Johnson Enterprise Innovation
Deal Size : Undisclosed
Deal Type : Collaboration
Shasqi Announces Research Collaboration to Transform Targeted Cancer Treatment
Details : Through the collaboration, Shasqi will apply its novel tumor-targeted CAPAC® platform to the development of new cancer therapies and will focus on Shasqi’s SQ3370, consisting of SQL70, a protodrug-activating biopolymer, and SQP33, a protodrug of Doxor...
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 01, 2023
Lead Product(s) : SQL70,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Johnson & Johnson Enterprise Innovation
Deal Size : Undisclosed
Deal Type : Collaboration
Details : SQ3370 is the first click chemistry-based treatment to be tested in humans, utilizes Shasqi’s proprietary CAPAC platform, an approach that activates cancer drugs at a tumor with decreased systemic toxicity.
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 17, 2022
Lead Product(s) : SQP33,SQL70
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Arcus Biosciences
Deal Size : $50.0 million
Deal Type : Series B Financing
Details : The funds will be used to advance the Phase 1/2 clinical study of SQ3370 for the treatment of injectable, advanced solid tumors, and will enable Shasqi to expand its click chemistry platform to create therapeutics that do not require intratumoral injecti...
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 11, 2021
Lead Product(s) : SQP33,SQL70
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Arcus Biosciences
Deal Size : $50.0 million
Deal Type : Series B Financing
Shasqi to Present Data Updates at Upcoming SITC and CTOS Meetings
Details : Presentations include updated data from Phase 1 study of SQ3370 in patients with advanced solid tumors and nonclinical data on SQ3370 combined with cancer immunotherapies. SQ3370 utilizes Shasqi’s proprietary CAPAC platfor that activates cancer drugs w...
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 04, 2021
Lead Product(s) : SQP33,SQL70
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Details : The grant will support immune biomarker analysis of patient samples from Shasqi’s Phase 1 clinical trial of lead candidate SQ3370 as well as manufacturing process development.
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 27, 2021
Lead Product(s) : SQP33,SQL70
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Details : SQ3370 is a novel investigational product that activates a non-toxic protodrug into a powerful chemotherapy agent, doxorubicin, precisely at a pre-injected tumor.
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 14, 2020
Details : The study, titled “SQ3370, a Local Activation Therapy of Cytotoxic Agents, Produces Sustained Responses in Target and Distal Lesions via Immune Activation,” was presented in a poster with audio at the American Association for Cancer Research Virtual ...
Brand Name : SQ3370
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 22, 2020
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