Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tagitanlimab,Cisplatin,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Kelun-Biotech's Tagitanlimab Approved for Second Indication in Recurrent NPC Treatment
Details : KL-A167 (tagitanlimab) is a PD-L1 inhibitor, is being investigated in combination with cisplatin and gemcitabine for the first-line treatment of recurrent or metastatic nasopharyngeal cancer (NPC).
Product Name : KL-A167
Product Type : Antibody
Upfront Cash : Inapplicable
January 23, 2025
Lead Product(s) : Tagitanlimab,Cisplatin,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Sacituzumab Tirumotecan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Grants Breakthrough Designation to Sacituzumab for Advanced NSCLC with EGFR Mutations
Details : SKB264 (sacituzumab tirumotecan) is a TROP-2 targeting ADC, being investiated in adult with epidermal growth factor receptor (EGFR)-mutant locally advanced or metastatic non-small cell lung cancer.
Product Name : SKB264
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
December 03, 2024
Lead Product(s) : Sacituzumab Tirumotecan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Sacituzumab Tirumotecan
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Kelun-Biotech's Sacituzumab Tirumotecan Approved in China for Advanced TNBC
Details : Sac-TMT (sacituzumab tirumotecan) is a TROP2-directed antibody–drug conjugate which is indicated for the treatment of adult patients with unresectable locally advanced or metastatic TNBC.
Product Name : SKB264
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
November 27, 2024
Lead Product(s) : Sacituzumab Tirumotecan
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Kelun-Biotech’s SKB264 NDA Accepted for Advanced EGFR-Mutant NSCLC
Details : SKB264 (sacituzumab tirumotecan) is a TROP-2 targeting ADC, being investiated in adult with epidermal growth factor receptor (EGFR)-mutant locally advanced or metastatic non-small cell lung cancer.
Product Name : SKB264
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
October 31, 2024
Kelun-Biotech's TROP2-ADC SKB264 NDA Accepted for Advanced NSCLC
Details : SKB264 (sacituzumab tirumotecan) is being evaluated in late-stage clinical trial studies with locally advanced or metastatic epidermal growth factor receptor-mutant non-small cell lung cancer.
Product Name : SKB264
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 20, 2024
Lead Product(s) : A166
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Levena Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A166 is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody conjugated to Duostatin-5, a novel anti-microtubule Auristatin derivative, via a proprietary stable covalent linker.
Product Name : A166
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
June 01, 2022
Lead Product(s) : A166
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Levena Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : A166
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Levena Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A166, a third-generation antibody-drug conjugate with tubulin inhibitor Duo-5 toxin, cleavable linker and site-specific K-Lock conjugation chemistry, demonstrated antitumor activity with meaningful responses in heavily pretreated subjects with HER2-posit...
Product Name : A166
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
May 03, 2022
Lead Product(s) : A166
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Levena Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable