Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SKB571
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Merck & Co
Deal Size : $37.5 million
Deal Type : Licensing Agreement
Merck & Co. Buys Kelun ADC For $37.5M, Drops Another Asset
Details : Merck has taken up its option on SKB571, a bispecific ADC that Kelun sees primarily as a treatment of solid tumors such as lung cancer and gastrointestinal tumors.
Brand Name : SKB571
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 20, 2024
Lead Product(s) : SKB571
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Merck & Co
Deal Size : $37.5 million
Deal Type : Licensing Agreement
Lead Product(s) : A166
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Levena Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A166 is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody conjugated to Duostatin-5, a novel anti-microtubule Auristatin derivative, via a proprietary stable covalent linker.
Brand Name : A166
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 01, 2022
Lead Product(s) : A166
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Levena Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Macromolecule-based Therapeutic
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Merck & Co
Deal Size : $1,407.0 million
Deal Type : Licensing Agreement
China’s Kelun Pharma Jumps on Licensing New Cancer Drug to Holland’s Merck Sharp & Dohme
Details : The deal, first disclosed Monday on the Shenzhen stock exchange, has Merck handing of upfront cash in exchange for ex-China rights to a “macromolecular tumor project".
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $47.0 million
May 16, 2022
Lead Product(s) : Macromolecule-based Therapeutic
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Merck & Co
Deal Size : $1,407.0 million
Deal Type : Licensing Agreement
Lead Product(s) : A166
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Levena Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A166, a third-generation antibody-drug conjugate with tubulin inhibitor Duo-5 toxin, cleavable linker and site-specific K-Lock conjugation chemistry, demonstrated antitumor activity with meaningful responses in heavily pretreated subjects with HER2-posit...
Brand Name : A166
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 03, 2022
Lead Product(s) : A166
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Levena Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
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