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Find Clinical Drug Pipeline Developments & Deals by Sichuan Kelun Pharmaceutical

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Merck has taken up its option on SKB571, a bispecific ADC that Kelun sees primarily as a treatment of solid tumors such as lung cancer and gastrointestinal tumors.

                          Brand Name : SKB571

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 20, 2024

                          Lead Product(s) : SKB571

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Merck & Co

                          Deal Size : $37.5 million

                          Deal Type : Licensing Agreement

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : A166 is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody conjugated to Duostatin-5, a novel anti-microtubule Auristatin derivative, via a proprietary stable covalent linker.

                          Brand Name : A166

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 01, 2022

                          Lead Product(s) : A166

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Levena Biopharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The deal, first disclosed Monday on the Shenzhen stock exchange, has Merck handing of upfront cash in exchange for ex-China rights to a “macromolecular tumor project".

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : $47.0 million

                          May 16, 2022

                          Lead Product(s) : Macromolecule-based Therapeutic

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Merck & Co

                          Deal Size : $1,407.0 million

                          Deal Type : Licensing Agreement

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : A166, a third-generation antibody-drug conjugate with tubulin inhibitor Duo-5 toxin, cleavable linker and site-specific K-Lock conjugation chemistry, demonstrated antitumor activity with meaningful responses in heavily pretreated subjects with HER2-posit...

                          Brand Name : A166

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 03, 2022

                          Lead Product(s) : A166

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Levena Biopharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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