Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Monoclonal Antibody-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Recipient : Vanderbilt University
Deal Size : Undisclosed
Deal Type : Licensing Agreement
SIGA Enters License with Vanderbilt for Novel Poxvirus Monoclonal Antibodies
Details : SIGA gains the exclusive rights for a portfolio of preclinical fully human mAbs which could be used as potential treatments for a broad range of orthopoxviruses, including smallpox and mpox.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 22, 2024
Lead Product(s) : Monoclonal Antibody-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Recipient : Vanderbilt University
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : U.S. Department of Defense
Deal Size : Undisclosed
Deal Type : Agreement
SIGA Awarded $9M U.S. Defense Contract For TPOXX Procurement
Details : The agreement aims for the procurement of Tpoxx (tecovirimat), an antiviral, approved in the US and Canada for the treatment of smallpox and authorized in EU and the UK for smallpox, mpox and cowpox.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 21, 2024
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : U.S. Department of Defense
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Topline Results from PALM 007 Study of SIGA’s Tecovirimat in Treatment of Mpox Released
Details : Tpoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Monkeypox Virus.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 15, 2024
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : ASEAN
Deal Size : Undisclosed
Deal Type : Divestment
SIGA Announces Agreement to Sell TPOXX® to ASEAN Member States
Details : The agreement aims to expand access to Tpoxx (tecovirimat), a novel small-molecule drug for the treatment of smallpox, to the member states in the ASEAN.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 17, 2024
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : ASEAN
Deal Size : Undisclosed
Deal Type : Divestment
Lead Product(s) : CLD-400
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : Calidi Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Calidi Collaborates with SIGA to Advance RTNova Virotherapy for Lung Cancer
Details : The collaboration aims to support the development of Calidi’s systemic and targeted RTNova (CLD-400) virotherapy platform, which has the potential to provide a universal treatment for all tumor types.
Brand Name : CLD-400
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 10, 2024
Lead Product(s) : CLD-400
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Calidi Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Recipient : Meridian Medical Technologies
Deal Size : Undisclosed
Deal Type : Agreement
SIGA Amends International Agreement for Oral TPOXX® Growth
Details : SIGA will lead international promotions for oral TPOXX, an FDA-approved drug for smallpox, while maintaining its contractual relationship with Meridian to ensure continuity for key customers.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : Meridian Medical Technologies
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TPOXX (tecovirimat), also known as tecovirimat and ST-246®, an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by variola virus.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2022
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vaccinia-based Cancer Therapy,Tecovirimat
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : KaliVir Immunotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
SIGA Announces Oncology Collaboration with KaliVir Immunotherapeutics
Details : TPOXX is a powerful antiviral drug to vaccinia and allows the safe use of higher doses of vaccinia vectors, there is also the potential it could increase immunotherapeutic outcomes.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 15, 2022
Lead Product(s) : Vaccinia-based Cancer Therapy,Tecovirimat
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : KaliVir Immunotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Catalent Pharma Solutions
Deal Size : Not Applicable
Deal Type : Not Applicable
SIGA Technologies Receives Approval from UK for Tecovirimat
Details : TPOXX (tecovirimat, ST-246®), a novel small-molecule drug, is an orthopoxvirus VP37 envelope wrapping protein inhibits the viral maturation of variola virus and other poxviruses by preventing the formation of a secondary viral envelope.
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 08, 2022
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Catalent Pharma Solutions
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Patheon
Deal Size : Not Applicable
Deal Type : Not Applicable
SIGA Receives Approval from the FDA for Intravenous (IV) Formulation of TPOXX® (tecovirimat)
Details : TPOXX®, also known as tecovirimat and ST-246®, an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by variola virus. TPOXX is a novel small-molecule drug and the US maintains a supply of TPOXX und...
Brand Name : Tpoxx
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 19, 2022
Lead Product(s) : Tecovirimat
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Patheon
Deal Size : Not Applicable
Deal Type : Not Applicable
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