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    [{"orgOrder":0,"company":"SIGA Technologies","sponsor":"U.S. Department of Defense","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Agreement","leadProduct":"Tecovirimat","moa":"Envelope phospholipase F13 (p37)","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"SIGA Technologies \/ U.S. Department of Defense","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ U.S. Department of Defense"},{"orgOrder":0,"company":"SIGA Technologies","sponsor":"BARDA","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Funding","leadProduct":"Tecovirimat","moa":"Envelope 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Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"SIGA Technologies \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ Inapplicable"}]

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                            01

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TEPOXX (tecovirimat) Approved in Japan for the Treatment of Orthopoxviruses

                            Details : Tepoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Orthopoxviruses.

                            Product Name : Tepoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 02, 2025

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Interim Results from STOMP Study of SIGA’s Tecovirimat in Treatment of Mpox Announced

                            Details : Tpoxx (tecovirimat) is an antiviral drug candidate that targets orthopoxvirus VP37 envelope wrapping protein. It is being evaluated for the treatment of mpox.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2024

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : U.S. Department of Defense

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            SIGA Awarded $9M U.S. Defense Contract For TPOXX Procurement

                            Details : The agreement aims for the procurement of Tpoxx (tecovirimat), an antiviral, approved in the US and Canada for the treatment of smallpox and authorized in EU and the UK for smallpox, mpox and cowpox.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 21, 2024

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : U.S. Department of Defense

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Topline Results from PALM 007 Study of SIGA’s Tecovirimat in Treatment of Mpox Released

                            Details : Tpoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Monkeypox Virus.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 15, 2024

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : ASEAN

                            Deal Size : Undisclosed

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            SIGA Announces Agreement to Sell TPOXX® to ASEAN Member States

                            Details : The agreement aims to expand access to Tpoxx (tecovirimat), a novel small-molecule drug for the treatment of smallpox, to the member states in the ASEAN.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 17, 2024

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : ASEAN

                            Deal Size : Undisclosed

                            Deal Type : Divestment

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                            06

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SIGA Provides Update on Progress in Clinical Trials to Assess Use of TPOXX ® (tecovirimat) for Treatment of M...

                            Details : TPOXX (tecovirimat), also known as tecovirimat and ST-246®, an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by variola virus.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2022

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : U.S. Department of Defense

                            Deal Size : $7.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            New Contract Awarded by U.S. Department of Defense for the Procurement of up to Approximately $7.5 Million of ...

                            Details : Tecovirimat (TPOXX) was approved by the European Medicines Agency (EMA) in January 2022 with a broader label that covers the treatment of smallpox, monkeypox, cowpox, and complications from vaccination for smallpox.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 05, 2022

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : U.S. Department of Defense

                            Deal Size : $7.5 million

                            Deal Type : Funding

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                            08

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Meridian Medical Technologies

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SIGA Technologies Receives Approval from the European Medicines Agency for Tecovirimat

                            Details : TPOXX (tecovirimat) receive EMA approval for use in the EU as an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by the variola virus.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 01, 2022

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Meridian Medical Technologies

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            SIGA Technologies

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                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Catalent Pharma Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SIGA Technologies Receives Approval from UK for Tecovirimat

                            Details : TPOXX (tecovirimat, ST-246®), a novel small-molecule drug, is an orthopoxvirus VP37 envelope wrapping protein inhibits the viral maturation of variola virus and other poxviruses by preventing the formation of a secondary viral envelope.

                            Product Name : Tpoxx

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 07, 2022

                            Lead Product(s) : Tecovirimat

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Catalent Pharma Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            SIGA Technologies

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                            Lead Product(s) : Undisclosed,Tecovirimat

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : KaliVir Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            SIGA Announces Oncology Collaboration with KaliVir Immunotherapeutics

                            Details : TPOXX is a powerful antiviral drug to vaccinia and allows the safe use of higher doses of vaccinia vectors, there is also the potential it could increase immunotherapeutic outcomes.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            July 15, 2022

                            Lead Product(s) : Undisclosed,Tecovirimat

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : KaliVir Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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