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    Find Clinical Drug Pipeline Developments & Deals by Sigilon Therapeutics

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                            01

                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-002

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : $344.2 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Lilly Completes Acquisition of Sigilon Therapeutics

                            Details : Through the acquisition, Lilly gains control of the partnered encapsulated cell therapies, including SIG-002 (human insulin), for the treatment of type 1 diabetes.

                            Brand Name : SIG-002

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $344.2 million

                            August 14, 2023

                            Lead Product(s) : SIG-002

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : $344.2 million

                            Deal Type : Acquisition

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                            02

                            Sigilon Therapeutics

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                            Antibody Engineering
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                            Sigilon Therapeutics

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                            Lead Product(s) : Insulin Lispro

                            Therapeutic Area : Endocrinology

                            Study Phase : Discovery

                            Sponsor : Eli Lilly

                            Deal Size : $344.2 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Lilly to Acquire Sigilon Therapeutics

                            Details : Through the acquisition, Lilly will gain control of the partnered encapsulated cell therapies, including SIG-002 (human insulin), for the treatment of type 1 diabetes.

                            Brand Name : SIG-002

                            Molecule Type : Peptide

                            Upfront Cash : $344.2 million

                            June 29, 2023

                            Lead Product(s) : Insulin Lispro

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Discovery

                            Sponsor : Eli Lilly

                            Deal Size : $344.2 million

                            Deal Type : Acquisition

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                            03

                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sigilon Therapeutics to Present Preclinical Data at the 18th Annual WORLDSymposium™ on Lysosomal Diseases, M...

                            Details : SIG-005 contains a human cell line genetically modified with a non-viral vector designed to express human a-L-iduronidase (IDUA), an enzyme which is missing or defective in patients with MPS-1.

                            Brand Name : SIG-005

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 31, 2022

                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Sigilon Therapeutics

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                            Antibody Engineering
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                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sigilon Preclinical Data International Symposium on MPS and Related Diseases

                            Details : Sigilon recently filed a Clinical Trial Application (CTA) in the United Kingdom for SIG-005 in MPS-1 and anticipates submitting an Investigational New Drug (IND) application and a CTA in the United States and Brazil, respectively.

                            Brand Name : SIG-005

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            July 23, 2021

                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Sigilon Therapeutics

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                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sigilon Therapeutics Receives Orphan Drug Designation for SIG-005 for the Treatment of Mucopolysaccharidosis T...

                            Details : SIG-005 contains a human cell line genetically modified with a non-viral vector designed to express human a-L-iduronidase (IDUA), an enzyme which is missing or defective in patients with MPS-1.

                            Brand Name : SIG-005

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 17, 2020

                            Lead Product(s) : SIG-005

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-001

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Chronic Disease Biotech Sigilon Therapeutics Files for a $100 Million IPO

                            Details : Sigilon's lead candidate, SIG-001, is designed to prevent bleeding episodes in patients with Hemophilia A and recently began a Phase 1/2 trial.

                            Brand Name : SIG-001

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 13, 2020

                            Lead Product(s) : SIG-001

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            07

                            Sigilon Therapeutics

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                            Lead Product(s) : SIG-001

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Canada Pension Plan Investment Board

                            Deal Size : $80.3 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Sigilon Therapeutics Announces $80.3 Million Series B Financing to Advance

                            Details : The funding will support the first-in-human clinical trial of Sigilon’s novel encapsulated cell therapy for hemophilia A.

                            Brand Name : Undisclosed

                            Molecule Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 17, 2020

                            Lead Product(s) : SIG-001

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Canada Pension Plan Investment Board

                            Deal Size : $80.3 million

                            Deal Type : Series B Financing

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