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    [{"orgOrder":0,"company":"Silo Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Psilocybine","moa":"","graph1":"Neurology","graph2":"Undisclosed","graph3":"Silo Pharma","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Silo Pharma \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Silo Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Silo Pharma","sponsor":"Zylo Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Agreement","leadProduct":"Ketamine Hydrochloride","moa":"NMDA 3A","graph1":"Neurology","graph2":"Undisclosed","graph3":"Silo 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    Find Clinical Drug Pipeline Developments & Deals by Silo Pharma

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                            01

                            Silo Pharma

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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Silo Pharma Achieves Positive Outcomes in SP-26 Ketamine Implant Testing

                            Details : SP-26 is a ketamine HCl-based injectable dissolvable polymer implant beng investigated for the treatment of chronic pain and fibromyalgia.

                            Brand Name : SP-26

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 31, 2024

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Silo Pharma

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                            Lead Product(s) : SPC-15

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Silo Pharma Completes FDA Pre-IND Meeting for SPC-15 Development in PTSD

                            Details : SPC-15 IS a 5-HT4 receptor agonist small molecule drug candidate, which is currently being evaluated for the treatment of patients with post-traumatic stress disorder.

                            Brand Name : SPC-15

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 10, 2024

                            Lead Product(s) : SPC-15

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Preclinical

                            Sponsor : Sever Pharma Solutions

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Silo Pharma Expands Agreement with Sever Pharma for Ketamine Implant Therapeutic

                            Details : The agreement aims for scale-up extrusion of the Company’s SP-26, a ketamine-based injectable dissolvable polymer implant for the treatment of chronic pain and fibromyalgia.

                            Brand Name : SP-26

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            August 14, 2024

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Preclinical

                            Sponsor : Sever Pharma Solutions

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Silo Pharma

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                            Lead Product(s) : SPU-16

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : WuXi AppTec

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Silo Pharma Announces Partnership with Global CRO for CNS Homing Peptide

                            Details : Through the partnership, Silo Pharma will advance the development of the SPU-16 for an early-stage study, a central nervous system homing peptide targeting multiple sclerosis.

                            Brand Name : SPU-16

                            Molecule Type : Peptide

                            Upfront Cash : Undisclosed

                            August 07, 2024

                            Lead Product(s) : SPU-16

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : WuXi AppTec

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Silo Pharma

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                            Lead Product(s) : SPC-15

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Preclinical

                            Sponsor : Resyca BV Partner

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Silo Pharma and Resyca BV Partner on Device and CMC Development for PTSD Drug SPC-15

                            Details : The partnership aims to advance the development of Silo lead product SPC-15, a 5-HT4 receptor agonist, which is being evaluated for the treatment of post-traumatic stress disorder.

                            Brand Name : SPC-15

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 18, 2024

                            Lead Product(s) : SPC-15

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Preclinical

                            Sponsor : Resyca BV Partner

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            06

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                            Lead Product(s) : SPC-14

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Silo Pharma Secures Exclusive Global License for Alzheimer's Therapeutic

                            Details : Silo Pharma recently announced an exclusive license agreement for its lead drug candidate SPC-14, which is being evaluated in the treatment for Alzheimer disease.

                            Brand Name : SPC-14

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 16, 2024

                            Lead Product(s) : SPC-14

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            07

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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Preclinical

                            Sponsor : Zylo Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Psychedelics Company Silo Pharma Working on Time-Release and Dosage Ketamine Implant and Topical, Hoping to De...

                            Details : The agreement aims to create a time-release ketamine implant, SP-26, which blocks the activity of the N-methyl-D-aspartate receptor (NMDAR), to treat fibromyalgia and other chronic pain conditions.

                            Brand Name : SP-26

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 23, 2023

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Preclinical

                            Sponsor : Zylo Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            08

                            Silo Pharma

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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Silo Pharma Signs Agreement to Develop First-in-Class Ketamine Implant Therapeutic

                            Details : The agreement aims to study and develop a dosage and time-release ketamine implant for the treatment of fibromyalgia, alongside development of SP-26, company's novel time-release topical formulation of ketamine.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 14, 2023

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Silo Pharma

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                            Lead Product(s) : Psilocybine,Dexamethasone

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : University of Maryland

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Silo Pharma Announces Positive Study Results of SPU- 21 for Arthritis

                            Details : In the most recent phase of this ongoing animal study, tests were conducted to evaluate the disease-suppressive effects of an SPU-21 (psilocybin) peptide-guided anti-arthritis drug versus the drug alone.

                            Brand Name : SPU- 21

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 30, 2022

                            Lead Product(s) : Psilocybine,Dexamethasone

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : University of Maryland

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Silo Pharma

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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Columbia University

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Silo Pharma Enters into Sponsored Research Agreement with Columbia University to Develop Psychedelic Therapeut...

                            Details : Under the agreement, Silo has been granted an option to license psychedelics as a therapeutic currently under development, for Alzheimer’s disease.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 27, 2021

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Columbia University

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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