[{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"CIRM","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Funding","leadProduct":"AAV Immuno-gene Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Siren Biotechnology \/ CIRM","highestDevelopmentStatusID":"4","companyTruncated":"Siren Biotechnology \/ CIRM"},{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"Catalent Pharma Solutions","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Partnership","leadProduct":"AAV-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Siren Biotechnology \/ Siren Biotechnology","highestDevelopmentStatusID":"4","companyTruncated":"Siren Biotechnology \/ Siren Biotechnology"},{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"SRN-101","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Siren Biotechnology \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Siren Biotechnology \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Siren Biotechnology

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : SRN-101 is a recombinant adeno-associated viral (AAV) vector expressing an engineered cytokine, it is being investigated for the treatment of high-grade gliomas.

                          Brand Name : SRN-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 18, 2024

                          Lead Product(s) : SRN-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The partnership aims to support the development and manufacturing of Siren Biotechnology’s AAV immuno-gene therapies, being developed for the treatment of cancer.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 08, 2024

                          Lead Product(s) : AAV-based Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Catalent Pharma Solutions

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The funding will support the development of novel AAV immuno-gene therapies for cancer, which exhibited potent anti-tumor effects in preclinical models of brain cancer.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 01, 2023

                          Lead Product(s) : AAV Immuno-gene Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : CIRM

                          Deal Size : $4.0 million

                          Deal Type : Funding

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