Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Pfizer Inc
Deal Size : $155.0 million
Deal Type : Collaboration
Details : RV521 (sisunatovir) is an investigational orally administered fusion inhibitor designed to block RSV replication by inhibiting F-mediated fusion with the host cell. Sisunatovir is being evaluated for the potential treatment of RSV infection in pediatric ...
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : $20.0 million
December 19, 2022
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Pfizer Inc
Deal Size : $155.0 million
Deal Type : Collaboration
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Pfizer Inc
Deal Size : $525.0 million
Deal Type : Acquisition
Pfizer Completes Acquisition of ReViral
Details : ReViral brings to Pfizer a portfolio of promising therapeutic candidates, including RV521 (sisunatovir), an orally administered inhibitor designed to block fusion of the RSV virus to the host cell.
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 09, 2022
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Pfizer Inc
Deal Size : $525.0 million
Deal Type : Acquisition
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Pfizer Inc
Deal Size : $525.0 million
Deal Type : Acquisition
Pfizer to Acquire ReViral and Its Respiratory Syncytial Virus Therapeutic Candidates
Details : Proposed acquisition strengthens Pfizer’s capabilities in infectious disease research and development with a promising therapeutic candidates, including sisunatovir, an orally administered inhibitor designed to block fusion of the RSV virus to the host...
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 07, 2022
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Pfizer Inc
Deal Size : $525.0 million
Deal Type : Acquisition
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVIRAL1 study evaluate safety, tolerability, pharmacokinetic profile, antiviral effects, and clinical effect of single and multiple oral doses of sisunatovir in healthy infants between ages of 1 and 36 months hospitalized with RSV lower respiratory trac...
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 16, 2021
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : ReViral
Deal Size : $119.0 million
Deal Type : Collaboration
Details : Sisunatovir is ReViral’s lead small molecule for the treatment of RSV, currently in Phase 2 clinical studies in pediatric and adult immunocompromised patient populations.
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : $14.0 million
March 02, 2021
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : ReViral
Deal Size : $119.0 million
Deal Type : Collaboration
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : CR-CP Life Science Fund
Deal Size : $44.0 million
Deal Type : Series C Financing
ReViral Raises $44 Million in Series C Financing
Details : The proceeds from the financing will be used to support Phase 2 clinical development for sisunatovir, ReViral's wholly-owned fusion protein inhibitor, and to progress our N-protein replication inhibitor program into Phase 1.
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 25, 2020
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : CR-CP Life Science Fund
Deal Size : $44.0 million
Deal Type : Series C Financing
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Sisunatovir is the company’s most advanced product candidate, with two international multicentre Phase 2 clinical studies recently initiated in pediatric and high-risk adult patient populations.
Brand Name : RV521
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 04, 2020
Lead Product(s) : Sisunatovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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