Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : CVS Health
Deal Size : Undisclosed
Deal Type : Agreement
Zydus, CVS Caremark Agreement Adds Zituvio™, Zituvimet™, Zituvimet™ XR
Details : Under the agreement, CVS Health will add Zydus product to its template formulary such as Zituvio (sitagliptin). It is indicated for the treatment of type 2 diabetes mellitus in adults.
Product Name : Zituvio
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 07, 2025
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : CVS Health
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : DA-1241,Sitagliptin Phosphate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MetaVia Announces Positive Phase 2a Results for DA-1241 in Presumed MASH Patients
Details : ASC47 is an adipose-targeted THRβ selective small molecule agonist. It is being evaluated in combination with semaglutide for the treatment of obesity.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 18, 2024
Lead Product(s) : DA-1241,Sitagliptin Phosphate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sitagliptin Phosphate,Metformin
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
USFDA gives tentative approval to Lupin’s generic formulation to treat type 2 diabetes
Details : Janumet-Generic (sitagliptin & metformin HCl) is a DPP-4 inhibitor & biguanide FDC product indicated as adjunct to diet & exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Product Name : Janumet-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
November 28, 2024
Lead Product(s) : Sitagliptin Phosphate,Metformin
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : DA-1241,Sitagliptin Phosphate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NeuroBo Reports Positive DA-1241 Safety Data and Opens Enrollment for Phase 2a
Details : DA-1241, a GPR119 agonist, is in Phase 2 trials with sitagliptin, a DPP4 inhibitor, for steatohepatitis treatment.
Product Name : DA-1241
Product Type : Small molecule
Upfront Cash : Not Applicable
January 18, 2024
Lead Product(s) : DA-1241,Sitagliptin Phosphate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Cosmos Health
Deal Size : Undisclosed
Deal Type : Acquisition
Cosmos Health Enters into Definitive Agreement to Acquire Type-2 Diabetes Treatment DIABIT-IS X
Details : Through the acquisition, Cosmos will gain the license and rights for DIABIT-IS X, a drug that contains the active substance sitagliptin and is used in the treatment of type-2 diabetes.
Product Name : DIABIT-IS X
Product Type : Small molecule
Upfront Cash : Undisclosed
December 20, 2023
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Cosmos Health
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Zydus Receives USFDA Approval for ZITUVIO™ to Treat Adult Patients with Type 2 Diabetes Mellitus
Details : Zituvio (Sitagliptin) tablets A is a dipeptidyl peptidase-4 (DPP-4) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Product Name : Zituvio
Product Type : Small molecule
Upfront Cash : Not Applicable
October 20, 2023
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sitagliptin Phosphate,Pioglitazone,Metformin
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Akums Gets DCGI Nod for Triple Combination Diabetes Medication
Details : Sitagliptin, Pioglitazone & Metformin are combined for the treatment of diabetes. Metformin, coupled with the functional and corrective influence of pioglitazone on beta-cell and metabolic syndrome and the stability of Sitagliptin, make an effective solu...
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
July 27, 2023
Lead Product(s) : Sitagliptin Phosphate,Pioglitazone,Metformin
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Metformin,Dapagliflozin,Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : CUREator
Deal Size : $1.0 million
Deal Type : Financing
Details : GMRx4 is being developed to provide a synergistic effect from three best-in-class type 2 diabetes treatments – metformin, dapagliflozin and sitagliptin – and, in an ultra-low-dose, single pill formulation, aims to be a more effective, simpler and saf...
Product Name : GMRx4
Product Type : Small molecule
Upfront Cash : Undisclosed
July 20, 2022
Lead Product(s) : Metformin,Dapagliflozin,Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : CUREator
Deal Size : $1.0 million
Deal Type : Financing
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : Not Applicable
Deal Type : Not Applicable
Generics of MSD Diabetes Pill Set to Flood Market as Patent Expires
Details : Januvia (sitagliptin), a class of dipeptidyl peptidase (DPP4) inhibitors, is used with a proper diet and exercise program and possibly with other medications to control high blood sugar.
Product Name : Januvia
Product Type : Small molecule
Upfront Cash : Not Applicable
July 07, 2022
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Zent2U Announces Successful Pivotal BE Trial on Sitagliptin Development
Details : Sitagliptin is a DPP-4 inhibitor, which is believed to exert its actions in patients with type 2 diabetes by slowing the inactivation of incretin hormones.
Product Name : Sitagliptin-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2021
Lead Product(s) : Sitagliptin Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable