Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
SiteOne Reports Positive Phase 1 Data for STC-004, a NaV1.8 Pain Inhibitor
Details : STC-004 is an oral, highly selective NaV1.8 inhibitor under development for the treatment of acute and chronic peripheral pain.
Product Name : STC-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 04, 2025
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Novo Holdings
Deal Size : $100.0 million
Deal Type : Series C Financing
SiteOne Raises $100M Series C for Non-Opioid Pain Treatments Using Ion Modulators
Details : The financing will support the company in advancing its lead program, STC-004, a Nav1.8 blocker, which is being evaluated for the treatment of pain, cough, and other conditions.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Undisclosed
December 18, 2024
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Novo Holdings
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : $15.0 million
Deal Type : Funding
Details : The funding will be used for the development of SiteOne's selective NaV1.8 inhibitor, STC-004, an investigational, non-opioid treatment for acute and chronic pain conditions.
Product Name : STC-004
Product Type : Small molecule
Upfront Cash : Undisclosed
May 18, 2023
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : $15.0 million
Deal Type : Funding
Lead Product(s) : ST-2427
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the agreement, the companies will work together to advance potent and selective inhibitors of sodium ion channel 1.7 (NaV1.7) as non-opioid therapeutics for the treatment of pain.
Product Name : ST-2427
Product Type : Small molecule
Upfront Cash : Undisclosed
January 19, 2022
Lead Product(s) : ST-2427
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : National Institutes of Health
Deal Size : $1.7 million
Deal Type : Funding
SiteOne Therapeutics Announces $1.73M Grant from NIH/NHLBI and Adds Respiratory Advisory Team
Details : Funding will support the development of an inhaled formulation of SiteOne’s drug candidate for chronic cough through IND-enabling studies and toward the clinic.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Undisclosed
May 11, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : National Institutes of Health
Deal Size : $1.7 million
Deal Type : Funding