Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SKY-0515
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Skyhawk Therapeutics Reports Positive Phase 1 Results for SKY-0515 in Huntington’s Disease
Details : SKY-0515 is a small molecule RNA splicing modifier, designed to reduce the production of the mutated huntingtin protein. It is being evaluated for the treatment of huntington's disease.
Brand Name : SKY-0515
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 10, 2024
Lead Product(s) : SKY-0515
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Discovery
Sponsor : Ipsen
Deal Size : $1,800.0 million
Deal Type : Collaboration
Ipsen and Skyhawk Therapeutics Announce Rna Targeting Collaboration in Rare Diseases
Details : The collaboration aims to develop novel small molecules that modulate RNA for rare neurological diseases, including an option for Ipsen to acquire license for successful candidates.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 22, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Discovery
Sponsor : Ipsen
Deal Size : $1,800.0 million
Deal Type : Collaboration
Lead Product(s) : SKY-0515
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Skyhawk Advances to Multiple Ascending Dose Portion of SKY-0515 Phase 1 Study
Details : SKY-0515 is a small molecule RNA splicing modifier designed to reduce mutated huntingtin protein production, being evaluated for Huntington's disease treatment.
Brand Name : SKY-0515
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 28, 2024
Lead Product(s) : SKY-0515
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Skyhawk Announces Collaboration Agreement with Sanofi for Oncology and Immunology Targets
Details : Under the terms of agreement, Sanofi will leverage Skyhawk's proprietary SkySTAR™ platform to discover and develop novel small molecules that modulate RNA splicing to address challenging oncology and immunology targets.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $54.0 million
July 05, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery Platform
Sponsor : Vertex Pharmaceuticals
Deal Size : $2,240.0 million
Deal Type : Collaboration
Details : The collaboration leverages SkySTAR™ platform to discover and develop novel small molecule therapeutics that modulate RNA splicing which have the potential to transform the lives of patients with serious diseases.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $40.0 million
December 22, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery Platform
Sponsor : Vertex Pharmaceuticals
Deal Size : $2,240.0 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery
Sponsor : Merck & Co
Deal Size : $600.0 million
Deal Type : Collaboration
Details : Under the expanded collaboration, Skyhawk will deploy its SkySTARTM platform to develop drug candidates directed to multiple new targets for autoimmune and metabolic diseases. The collaboration now spans neurodegeneration, oncology, autoimmunity, and met...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 12, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery
Sponsor : Merck & Co
Deal Size : $600.0 million
Deal Type : Collaboration
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