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Find Clinical Drug Pipeline Developments & Deals for Sodium Zirconium Cyclosilicate

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                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Lokelma (sodium zirconium cyclosilicate) is an anti-hyperkalaemia (HK) therapy that provides rapid potassium reduction and sustained potassium control.15 It is indicated for the treatment of Hyperkalaemia (HK) in adults.

                          Brand Name : Lokelma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 01, 2023

                          Lead Product(s) : Sodium Zirconium Cyclosilicate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Lokelma (sodium zirconium cyclosilicate) is an anti-hyperkalaemia (HK) therapy that provides rapid potassium reduction and sustained potassium control.15 It is indicated for the treatment of Hyperkalaemia (HK) in adults.

                          Brand Name : Lokelma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 02, 2023

                          Lead Product(s) : Sodium Zirconium Cyclosilicate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The designation is based on the potential of LOKELMA to reduce serious adverse CV outcomes in this patient population, addressing a significant unmet medical need.

                          Brand Name : Lokelma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 17, 2021

                          Lead Product(s) : Sodium Zirconium Cyclosilicate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The approval by the NMPA was based on data from the Phase IIIb DIALIZE trial. The trial showed sustained potassium control pre-dialysis for more patients receiving Lokelma, compared with placebo.

                          Brand Name : Lokelma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 24, 2020

                          Lead Product(s) : Sodium Zirconium Cyclosilicate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The 20 abstracts being presented, will include data on Lokelma (sodium zirconium cyclosilicate), roxadustat & Farxiga (dapagliflozin) across different stages of CKD and AstraZeneca’s ongoing commitment to exploring treatment options across the full con...

                          Brand Name : Lokelma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 05, 2020

                          Lead Product(s) : Sodium Zirconium Cyclosilicate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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