Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves Samsung Bioepis’ EPYSQLI® as Biosimilar to Soliris
Details : Epysqli (eculizumab) is a complement C5 inhibitor antibody which is indicated to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
Brand Name : Epysqli
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 22, 2024
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves First Interchangeable Biosimilar for Two Rare Diseases
Details : Bkemv (eculizumab) is approved by FDA as the first interchangeable biosimilar to Soliris to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
Brand Name : Bkemv
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 28, 2024
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Danicopan,Ravulizumab,Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Danicopan is an investigational oral medicine in development as an add-on to C5 inhibitor therapy eculizumab or ravulizumab for patients with paroxysmal nocturnal hemoglobinuria (PNH) who experience clinically significant extravascular haemolysis.
Brand Name : ALXN2040
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 11, 2023
Lead Product(s) : Danicopan,Ravulizumab,Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Soliris (eculizumab) is a first-in-class C5 complement inhibitor and is approved in Japan for the treatment of adults with Neuromyelitis Optica Spectrum Disorder.
Brand Name : Soliris
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 18, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Soliris Approved in Japan for Paediatric Patients with Generalised Myasthenia Gravis (gMG)
Details : Soliris (eculizumab) is a first-in-class C5 complement inhibitor and is approved in Japan for the treatment of adults with refractory generalised myasthenia gravis.
Brand Name : Soliris
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 24, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Soliris (eculizumab) is a first-in-class C5 complement inhibitor and is approved in China for the treatment of adults with refractory generalised myasthenia gravis.
Brand Name : Soliris
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 27, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Soliris (eculizumab) is a first-in-class C5 complement inhibitor and approved in China for the treatment of adults with refractory generalised myasthenia gravis.
Brand Name : Soliris
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 26, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Soliris Approved In China For The Treatment Of Adults With Refractory Generalised Myasthenia Gravis
Details : Soliris (eculizumab) is a first-in-class C5 complement inhibitor and approved in China for the treatment of adults with refractory generalised myasthenia gravis.
Brand Name : Soliris
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Danicopan,Eculizumab,Ravulizumab
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ALXN2040 (danicopan) is an investigational oral medicine in development as an add-on to standard of care C5 inhibitor therapy Ultomiris (ravulizumab) or Soliris (eculizumab) for patients with PNH who experience clinically significant EVH.
Brand Name : ALXN2040
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 09, 2023
Lead Product(s) : Danicopan,Eculizumab,Ravulizumab
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Samsung Bioepis Receives Positive CHMP Opinion for Eculizumab Biosimilar, EPYSQLI™
Details : Epysqli™ (eculizumab) is a mAb that specifically binds to the complement protein C5, thereby inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9 mediated intravascular hemolysis in PNH patients.
Brand Name : Epysqli
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 31, 2023
Lead Product(s) : Eculizumab
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?