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                          01

                          Cophex
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                          Details : Winrevair (sotatercept) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 30, 2025

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Cophex
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                          Cophex
                          Not Confirmed

                          Details : Winrevair (sotatercept) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          December 31, 2024

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Winrevair (sotatercept), an activin signaling inhibitor therapy, being evaluated for the treatment of adults with pulmonary arterial hypertension functional class III or IV at high risk of mortality.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          November 25, 2024

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Winrevair (sotatercept) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          August 26, 2024

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Winrevair (sotatercept-csrk) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          June 28, 2024

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Winrevair (sotatercept-csrk) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          March 26, 2024

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : MK-7962 (sotatercept) is a potential first-in-class activin signaling inhibitor biologic being studied for the treatment of adult patients with pulmonary arterial hypertension.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 28, 2023

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          08

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : MK-7962 (sotatercept), is an activin receptor type IIA fusion protein that acts as a ligand trap for members in the transforming growth factor-beta protein superfamily involved in remodeling and regeneration of a variety of different tissues like vascula...

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          June 03, 2023

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Sotatercept,is an investigational, potential first-in-class activin receptor type IIA-Fc fusion protein demonstrated significant improvement in exercise capacity and key secondary outcome measures compared to placebo when added to background therapy.

                          Product Name : Winrevair

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          October 10, 2022

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Cophex
                          Not Confirmed
                          Cophex
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                          Details : Through the successful completion of the acquisition of Acceleron Pharma, Merck would be growing its cardiovascular portfolio and pipeline, including Acceleron’s lead therapeutic candidate, sotatercept, has a novel mechanism of action with the potentia...

                          Product Name : ACE-011

                          Product Type : Protein

                          Upfront Cash : $11,500.0 million

                          November 19, 2021

                          Lead Product(s) : Sotatercept

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Merck & Co

                          Deal Size : $11,500.0 million

                          Deal Type : Acquisition

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