Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : $15.0 million
Deal Type : Financing
Pharmazz and Sun Pharma Partner for $15 Million Investment in Pharmazz
Details : The financing will support completion of Pharmazz's pivotal Phase 3 study for Tyvalzi (sovateltide) to treat patients with acute cerebral ischemic stroke.
Brand Name : Tyvalzi
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 21, 2024
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : $15.0 million
Deal Type : Financing
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Tycamzzi (Sovateltide), is a first-in-class drug and endothelin-B receptor agonist that increases blood flow and inhibits apoptosis, which is investigated for the treatment of acute cerebral ischemic stroke patients.
Brand Name : Tycamzzi
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 02, 2023
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Underf the agreement, Sun Pharma is granted rights for marketing Sovateltide in India under the brand name Tyvalzi, a selective endothelin B receptor agonist and a new first-in-class drug recently approved for treating cerebral ischemic stroke.
Brand Name : Tyvalzi
Molecule Type : Peptide
Upfront Cash : Undisclosed
September 13, 2023
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Sun Pharmaceutical Industries Limited
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Tycamzzi, a first-in-class drug and endothelin-B receptor agonist that increases blood flow and inhibits apoptosis, receives marketing approval in India for the treatment of acute cerebral ischemic stroke. Sovateltide is in Phase 3 trial in US for the sa...
Brand Name : Tycamzzi
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Tycamzzi (sovateltide) is a highly selective endothelin-B receptor agonist, having the potential to be a neuronal progenitor cell therapeutics with anti-apoptotic activity that improves cerebral blood flow and neurological outcome in acute cerebral ische...
Brand Name : Tycamzzi
Molecule Type : Peptide
Upfront Cash : Not Applicable
February 13, 2023
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results of this trial shows highly encouraged regarding the potential of Tycamzzi (sovateltide) to be the first therapeutic since tPA to demonstrate a positive impact on patients suffering from acute ischemic stroke.
Brand Name : Tycamzzi
Molecule Type : Peptide
Upfront Cash : Not Applicable
February 10, 2023
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PMZ-1620 (sovateltide) is an endothelin-B receptor agonist. PMZ-1620 has the potential to be a first-in-class neuronal progenitor cell therapeutics that is likely to promote quicker recovery and improve neurological outcome in cerebral ischemic stroke pa...
Brand Name : PMZ-1620
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 31, 2022
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Tycamzzi (sovateltide), an endothelin-B receptor agonist, has been previously shown to increase cerebral blood flow, have anti-apoptotic activity and produce neurovascular remodeling when administered IV following acute cerebral ischemic stroke in rats.
Brand Name : Tycamzzi
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 26, 2022
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PMZ-1620 (sovateltide) is endothelin-B receptor agonist that increases blood flow, shows anti-apoptotic activity, protects neural mitochondria, and produces neurovascular remodeling. Sovateltide is undergoing MA review by CDSCO for acute cerebral ischemi...
Brand Name : PMZ-1620
Molecule Type : Peptide
Upfront Cash : Not Applicable
August 29, 2022
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PMZ-1620 having Sovateltide as API, is the Company’s endothelin-B receptor agonist that is also in a Phase III trial for the treatment of cerebral ischemic stroke. In clinical trials, subjects will receive either three intravenous doses of sovateltide,...
Brand Name : PMZ-1620
Molecule Type : Peptide
Upfront Cash : Not Applicable
February 03, 2022
Lead Product(s) : Sovateltide
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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