[{"orgOrder":0,"company":"Amgen Inc","sponsor":"Volastra Therapeutics","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Volastra Therapeutics In-Licenses Clinical Stage KIF18A Inhibitor and Secures $60 Million in Series A Funding to Further Advance Cancer-Focused Pipeline","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"March 2023","year":"2023","type":"Licensing Agreement","leadProduct":"Sovilnesib","moa":"","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I","graph3":"Amgen Inc","amount2":0,"therapeuticAreaNew":"Oncology","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","productSubType":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Amgen Inc \/ Volastra Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Amgen Inc \/ Volastra Therapeutics"},{"orgOrder":0,"company":"Volastra Therapeutics","sponsor":"Polaris Partners","pharmaFlowCategory":"D","amount":"$60.0 million","upfrontCash":"Undisclosed","newsHeadline":"Volastra Therapeutics In-Licenses Clinical Stage KIF18A Inhibitor and Secures $60 Million in Series A Funding to Further Advance Cancer-Focused Pipeline","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"March 2023","year":"2023","type":"Series A Financing","leadProduct":"Sovilnesib","moa":"","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I","graph3":"Volastra Therapeutics","amount2":0.059999999999999998,"therapeuticAreaNew":"Oncology","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","productSubType":"","amount2New":0.059999999999999998,"dosageForm":"Tablet","sponsorNew":"Volastra Therapeutics \/ Polaris Partners","highestDevelopmentStatusID":"6","companyTruncated":"Volastra Therapeutics \/ Polaris Partners"},{"orgOrder":0,"company":"Volastra Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Volastra Therapeutics Announces First Patient Dosed in Phase Ib Clinical Trial of Sovilnesib","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"April 2024","year":"2024","type":"Not Applicable","leadProduct":"Sovilnesib","moa":"","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I","graph3":"Volastra Therapeutics","amount2":0,"therapeuticAreaNew":"Oncology","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","productSubType":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Volastra Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Volastra Therapeutics \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for Sovilnesib

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                          Top Deals by Deal Size (USD bn)

                          01

                          IPEX Indonesia
                          Not Confirmed
                          IPEX Indonesia
                          Not Confirmed

                          Details : AMG-650 (sovilnesib) is a KIF18A inhibitor, small molecule drug candidate, which is being evaluated for the treatment of patients with platinum-resistant or refractory high-grade serous ovarian cancer.

                          Brand Name : AMG-650

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 16, 2024

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          IPEX Indonesia
                          Not Confirmed
                          IPEX Indonesia
                          Not Confirmed

                          Details : Under the terms of the licensing agreement, Volastra receives an exclusive worldwide license (ex-China) to develop and commercialize AMG650 (sovilnesib), an oral, first-in-class small molecule inhibitor of KIF18A.

                          Brand Name : AMG650

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 07, 2023

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Volastra Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          IPEX Indonesia
                          Not Confirmed
                          IPEX Indonesia
                          Not Confirmed

                          Details : The Funding will support clinical development of Volastra’s portfolio of KIF18A inhibitors including, AMG650 (sovilnesib), an oral, first-in-class small molecule, as well as advancement of a robust pipeline of research programs targeting chromosomally ...

                          Brand Name : AMG650

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 07, 2023

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Polaris Partners

                          Deal Size : $60.0 million

                          Deal Type : Series A Financing

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