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    [{"orgOrder":0,"company":"SparingVision","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Peptide","year":"2020","type":"Agreement","leadProduct":"Teriparatide","moa":"PTH receptor","graph1":"Musculoskeletal","graph2":"Approved","graph3":"SparingVision","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"SparingVision \/ Undisclosed","highestDevelopmentStatusID":"12","companyTruncated":"SparingVision \/ Undisclosed"},{"orgOrder":0,"company":"SparingVision","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"FRANCE","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"SPVN06","moa":"","graph1":"Genetic 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                            01

                            SparingVision

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            SparingVision Completes Final Dose Escalation in PRODYGY Trial with SPVN06

                            Details : SPVN06 is a mutation-agnostic AAV gene therapy approach comprising one neurotrophic factor (RdCVF) and one enzyme reducing oxidative stress. It is under development for treating Retinitis Pigmentosa.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 24, 2024

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            SparingVision Reports Positive Initial Safety Data from the first cohort treated in its PRODYGY Phase I/II Gen...

                            Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress used for the treatment of for the treatment of retinitis pigmentosa.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            August 30, 2023

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : SPVN20

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Tenpoint Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            SparingVision Sells Ex Vivo GIRK Technology to Tenpoint Therapeutics

                            Details : Through the divestment, Tenpoint has acquired SparingVision's ex vivo GIRK technology. SparingVision will remain focused on in vivo genomic medicines, with SPVN20, a GIRK-based gene therapy candidate.

                            Brand Name : SPVN20

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 12, 2023

                            Lead Product(s) : SPVN20

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Tenpoint Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Divestment

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                            04

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            SparingVision's Lead Asset SPVN06 Clears IND Application in the US for the Treatment of Retinitis Pigmentosa

                            Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress which, acting synergistically, aim at slowing or stopping the degeneration of cone photoreceptors.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 01, 2022

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Jeito Capital

                            Deal Size : $75.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            SparingVision Raises €75 Million Series B to Continue Building World-Leading Portfolio of Genomic Medicines ...

                            Details : Proceeds from the financing will be used to fund the first-in-human trials of the Company’s two lead gene-independent assets, SPVN06 and SPVN20, as well as the development of genome editing assets through its collaboration with Intellia Therapeutics.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 14, 2022

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Jeito Capital

                            Deal Size : $75.0 million

                            Deal Type : Series B Financing

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                            06

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                            Lead Product(s) : SPVN50

                            Therapeutic Area : Ophthalmology

                            Study Phase : Discovery

                            Recipient : Intellia Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Intellia Therapeutics and SparingVision Announce Strategic Collaboration to Develop Novel Ocular Therapies Usi...

                            Details : As part of this collaboration, Intellia will grant SparingVision exclusive rights to Intellia’s proprietary in vivo CRISPR/Cas9-based genome editing technology including SPVN50 for up to three ocular targets addressing diseases with significant unmet m...

                            Brand Name : SPVN50

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            October 13, 2021

                            Lead Product(s) : SPVN50

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Discovery

                            Recipient : Intellia Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

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                            Lead Product(s) : SPVN20

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Recipient : GAMUT Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            SparingVision Expands Novel Ocular Disease Pipeline with Acquisition of GAMUT Therapeutics

                            Details : Acquisition adds unique gene-independent approach to treat the later stages of rod-cone dystrophies such as retinitis pigmentosa. GAMUT’s lead product, now SPVN20, is a novel, mutation-agnostic gene therapy, which aims at restoring the function of dorm...

                            Brand Name : SPVN20

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 20, 2021

                            Lead Product(s) : SPVN20

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Recipient : GAMUT Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            08

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Recipient : Agtc

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            AGTC licenses Promoter Technology to SparingVision SAS

                            Details : Under the terms of the agreement, SparingVision SAS receives nonexclusive rights to AGTC’s PR1.7 promoter for use in the development of two non-competing products with an opportunity to obtain rights to use the promoter for one additional product in th...

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 19, 2021

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Recipient : Agtc

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            SparingVision

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : 4BIO Capital

                            Deal Size : $51.9 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            SparingVision Raises €44.5 Million and Appoints Stéphane Boissel as Chief Executive Officer

                            Details : Proceeds from the financing will be primarily used to advance the development of SparingVision’s breakthrough treatment SPVN06 for the mutation-agnostic treatment of retinitis pigmentosa.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            October 21, 2020

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : 4BIO Capital

                            Deal Size : $51.9 million

                            Deal Type : Financing

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                            10

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                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            SparingVision Receives European Orphan Designation for its Drug Candidate SPVN06 Dedicated to Inherited Retina...

                            Details : SPVN06 uses a gene therapy-based approach independent of mutated genes and by a single subretinal injection of proprietary neurotrophic factors, aims at stopping and preventing the degeneration of photoreceptors leading to blindness.

                            Brand Name : SPVN06

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 30, 2020

                            Lead Product(s) : SPVN06

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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