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    [{"orgOrder":0,"company":"SparX Biopharmaceutical","sponsor":"Arovella Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Collaboration","leadProduct":"SPX-101","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"SparX Biopharmaceutical","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"SparX Biopharmaceutical \/ Arovella Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"SparX Biopharmaceutical \/ Arovella Therapeutics"},{"orgOrder":0,"company":"SparX Biopharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"SPX-303","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"SparX Biopharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"SparX Biopharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"SparX Biopharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"SparX Biopharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"SPX-303","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"SparX Biopharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"SparX Biopharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"SparX Biopharmaceutical \/ Not Applicable"}]

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                            Lead Product(s) : SPX-303

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            SparX Doses First Patient with SPX-303, an anti-LILRB2/PD-L1 Bispecific Antibody

                            Details : SPX-303 is a bispecific antibody therapy targeting LILRB2 and PD-L1, under investigation for various solid tumors treatment.

                            Brand Name : SPX-303

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 11, 2024

                            Lead Product(s) : SPX-303

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : SPX-303

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            SparX Biopharmaceutical Announces FDA Greenlight for IND Application of SPX-303, A First-In-Human anti-LILRB2/...

                            Details : SPX-303 is a First-in-Its Class bispecific antibody therapy, ingeniously engineered to engage two cardinal immune checkpoint proteins, LILRB2 and PD-L1, simultaneously.

                            Brand Name : SPX-303

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 30, 2023

                            Lead Product(s) : SPX-303

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : SPX-101

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Arovella Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            The SparX Group Enters into a Collaboration with Arovella Therapeutics for the Development of CLDN18.2-CAR-iNK...

                            Details : The collaboration aims for the utilization of SPX-101, an innovative monoclonal antibody (mAb) that targets the Claudin 18.2 (CLDN18.2) tumor specific antigen, as an exciting component in Arovella's CLDN18.2-CAR-iNKT cells as a leading off-the-shelf CAR-...

                            Brand Name : SPX-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            October 10, 2023

                            Lead Product(s) : SPX-101

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Arovella Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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