7
ALL7
StaliclaYear
7
ALL2
20243
20231
20221
2020DEALS // DEV.
7
ALL4
Deals3
DevelopmentsCountry
7
ALL7
SWITZERLAND7
ALL1
Firefly Neuroscience3
Inapplicable1
National Institute on Drug Abuse1
Novartis Pharmaceuticals Corporation1
SPRIM Global investmentsTherapeutic Area
7
ALL4
Neurology3
Psychiatry/PsychologyStudy Phase
7
ALL3
Phase II4
Phase IDeal Type
7
ALL1
Agreement3
Inapplicable1
Licensing Agreement1
Partnership1
Series B FinancingProduct Type
7
ALL7
Other Small MoleculeDosage Form
7
ALL4
Oral Capsule3
Oral TabletLead Product
7
ALL4
Ibudilast3
MavoglurantTarget
7
ALL4
PDE43
mGluR5Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
STALICLA Starts Phase 3 DDI Study of STP7 to Treat Cocaine Use Disorder in the U.S.
Details : STP7 (Mavoglurant) is the most clinically advanced negative allosteric modulator of the glutamate receptor 5 (mGluR5 NAM). It is being evaluated for the treatment of cocaine use disorder.
Product Name : STP7
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 05, 2024
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : SPRIM Global investments
Deal Size : $17.4 million
Deal Type : Series B Financing
Stalicla Secures $17.4 Million Series B Financing for Precision Neuro Advancements
Details : Proceeds will support Stalicla's phase 2 Autism Spectrum Disorder (ASD) trial for STP1, a fixed-dose combination of PDE4/3 inhibitor (ibudilast) and NKCC1 antagonist (bumetanide).
Product Name : STP1
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 16, 2024
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : SPRIM Global investments
Deal Size : $17.4 million
Deal Type : Series B Financing
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $270.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, STALICLA has acquired worldwide rights to AFQ056 (mavoglurant) for substance-use disorders, neurodevelopmental disorders, and other indications. Mavoglurant is a selective non allosteric metabotropic glutamate receptor 5...
Product Name : STP7
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 01, 2023
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $270.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement covers the clinical development program of STP7 (mavoglurant) to treat patients diagnosed with cocaine use disorder (CUD), including a Phase 3 study.
Product Name : STP7
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 03, 2023
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Firefly Neuroscience
Deal Size : Undisclosed
Deal Type : Partnership
Details : STALICLA and Firefly will leverage their technological platforms including the DEPI and BNA platform respectively to further advance EEG validation in two upcoming Phase 2 clinical trials including STALICLA’s lead asset STP1, a tailored treatment candi...
Product Name : STP1
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 27, 2023
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Firefly Neuroscience
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In addition to showing good safety and tolerability profile, and dose-dependent target engagement, STP1 treatment resulted in positive signals in clinical markers of neurological and behavioral function, including improved processing speed and crystalliz...
Product Name : STP1
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 24, 2022
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : STP1 is a novel combination of compounds: a pan-PDE inhibitor with anti-inflammatory properties and a modulator of NKCC1, specifically targeting the biological dysregulations linked to ASD-Phen1.
Product Name : STP1
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 12, 2020
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable