Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
STALICLA Starts Phase 3 DDI Study of STP7 to Treat Cocaine Use Disorder in the U.S.
Details : STP7 (Mavoglurant) is the most clinically advanced negative allosteric modulator of the glutamate receptor 5 (mGluR5 NAM). It is being evaluated for the treatment of cocaine use disorder.
Brand Name : STP7
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 02, 2024
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : SPRIM Global Investments
Deal Size : $17.4 million
Deal Type : Series B Financing
Stalicla Secures $17.4 Million Series B Financing for Precision Neuro Advancements
Details : Proceeds will support Stalicla's phase 2 Autism Spectrum Disorder (ASD) trial for STP1, a fixed-dose combination of PDE4/3 inhibitor (ibudilast) and NKCC1 antagonist (bumetanide).
Brand Name : STP1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 16, 2024
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : SPRIM Global Investments
Deal Size : $17.4 million
Deal Type : Series B Financing
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Firefly Neuroscience
Deal Size : Undisclosed
Deal Type : Partnership
Details : STALICLA and Firefly will leverage their technological platforms including the DEPI and BNA platform respectively to further advance EEG validation in two upcoming Phase 2 clinical trials including STALICLA’s lead asset STP1, a tailored treatment candi...
Brand Name : STP1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 27, 2023
Lead Product(s) : Ibudilast,Bumetanide
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Firefly Neuroscience
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement covers the clinical development program of STP7 (mavoglurant) to treat patients diagnosed with cocaine use disorder (CUD), including a Phase 3 study.
Brand Name : STP7
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 08, 2023
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $270.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, STALICLA has acquired worldwide rights to AFQ056 (mavoglurant) for substance-use disorders, neurodevelopmental disorders, and other indications. Mavoglurant is a selective non allosteric metabotropic glutamate receptor 5...
Brand Name : AFQ056
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $270.0 million
Deal Type : Licensing Agreement
Lead Product(s) : STP1
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In addition to showing good safety and tolerability profile, and dose-dependent target engagement, STP1 treatment resulted in positive signals in clinical markers of neurological and behavioral function, including improved processing speed and crystalliz...
Brand Name : STP1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 24, 2022
Lead Product(s) : STP1
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : STP1
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : STP1 is a novel combination of compounds: a pan-PDE inhibitor with anti-inflammatory properties and a modulator of NKCC1, specifically targeting the biological dysregulations linked to ASD-Phen1.
Brand Name : STP1
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
December 11, 2020
Lead Product(s) : STP1
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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