Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Insilico Medicine
Deal Size : $512.0 million
Deal Type : Licensing Agreement
Menarini Group Signs Exclusive License for KAT6 Inhibitor for Breast Cancer
Details : Stemline will have global rights to develop a novel KAT6A inhibitor designed using Insilico’s AI platform, targeting hormone-sensitive cancers and other oncology indications.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $12.0 million
January 04, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Insilico Medicine
Deal Size : $512.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Elacestrant
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Orserdu (elacestrant) is an estrogen receptor antagonist that binds to estrogen receptor-alpha (ERα). It inhibits 17β-estradiol mediated cell proliferation at concentrations inducing degradation of ERα protein mediated through proteasomal pathway.
Brand Name : Orserdu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 30, 2023
Lead Product(s) : Elacestrant
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Menarini
Deal Size : $677.0 million
Deal Type : Acquisition
Menarini Group Completes Acquisition of Stemline Therapeutics
Details : Acquisition establishes Menarini’s presence in the U.S. biopharmaceutical oncology market. Menarini will support further development of Stemline’s ELZONRIS and enable global expansion by leveraging its commercial infrastructure in Europe and other ex...
Brand Name : Elzonris
Molecule Type : Large molecule
Upfront Cash : $677.0 million
June 10, 2020
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Menarini
Deal Size : $677.0 million
Deal Type : Acquisition
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Menarini
Deal Size : $677.0 million
Deal Type : Acquisition
Menarini Group to Acquire Stemline Therapeutics in Transaction Valued at Up to $677 Million
Details : With the support of Menarini’s infrastructure, Stemline will continue its efforts to develop new applications of ELZONRIS to meet unmet needs of patients with difficult to treat diseases and cancers.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $677.0 million
May 04, 2020
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Menarini
Deal Size : $677.0 million
Deal Type : Acquisition
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A Phase 1/2 trial of ELZONRIS in combination with other agents in patients with relapsed/refractory AML, treatment-naive AML unfit for chemotherapy, and high-risk myelodysplastic syndrome (MDS) is currently enrolling patients.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 13, 2020
Lead Product(s) : Tagraxofusp
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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