Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Burning Rock Dx
Deal Size : Not Applicable
Deal Type : Not Applicable
NMPA Grants Approval For NGS-Based Companion Diagnostic For Lung Cancer
Details : DZD9008 (sunvozertinib) is an oral, potent, irreversible, & selective EGFR tyrosine kinase inhibitor. It is indicated for the treatment of Exon20ins-mutated locally advanced or metastatic NSCLC.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 10, 2024
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Burning Rock Dx
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
WU-KONG1B Study Shows Sunvozertinib Efficacy in EGFR Exon 20 NSCLC
Details : DZD9008 (sunvozertinib) is an oral, potent, irreversible, & selective EGFR tyrosine kinase inhibitor. It is being evaluated for the treatment of Exon20ins-mutated locally advanced or metastatic NSCLC.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 16, 2024
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sunvozertinib Meets Primary Endpoint in NSCLC with EGFR Exon 20 Insertions
Details : DZD9008 (sunvozertinib) is an oral, potent, irreversible, & selective EGFR tyrosine kinase inhibitor. It is being evaluated for the treatment of Exon20ins-mutated locally advanced or metastatic NSCLC.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 02, 2024
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Dizal Highlights Sunvozertinib's Efficacy for Lung Cancer with EGFR Exon 20 Mutations
Details : DZD9008 (sunvozertinib) is an oral, potent, irreversible, & selective EGFR tyrosine kinase inhibitor. It is being evaluated for the treatment of Exon20ins-mutated locally advanced or metastatic NSCLC.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 24, 2024
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Grants Breakthrough Designation to Sunvozertinib for NSCLC Treatment
Details : DZD9008 (sunvozertinib), an EGFR tyrosine kinase inhibitor, is being studied for Exon20ins-mutated advanced non-small cell lung cancer.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 07, 2024
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Dizal Pharmaceutical
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership aims to accelerate the development of DZD9008 (sunvozertinib), an irreversible EGFR inhibitor discovered by Dizal scientists targeting a wide spectrum of EGFR mutations with wild-type EGFR selectivity, for patients with EGFR Exon20ins mut...
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 06, 2023
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Dizal Pharmaceutical
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : DZD9008 (sunvozertinib) is an investigational, oral tyrosine kinase inhibitor (TKI) specifically designed to selectively target epidermal growth factor receptor (EGFR) exon20 insertion (exon20ins) mutations for the treatment of advanced NSCLC.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 10, 2023
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : DZD9008 (sunvozertinib) also demonstrated a favorable safety profile, Of all 277 patients in the safety set, the most common treatment-related adverse events were diarrhea and rash, the majority of which were Grade 1/2 and clinically manageable.
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 05, 2022
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Updated findings from the studies, in platinum-pretreated patients (n=119), the best ORR (at the RP2D of 300mg QD) assessment according to RECIST guidelines (version 1.1) was 52.4%. In patients with baseline brain metastasis, the best ORR at 300 mg QD re...
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 05, 2022
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Dizal to Demonstrate the Strength and Rapid Acceleration of its Clinical Portfolio at ASCO 2022
Details : Sunvozertinib (DZD9008) shows superior efficacy in NSCLC patients harboring EGFR exon 20 insertion mutations after platinum and anti-PD(L)1 treatment failures. It also demonstrates superior efficacy in patients after platinum and anti-PD(L)1 treatment fa...
Brand Name : DZD9008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 27, 2022
Lead Product(s) : Sunvozertinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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