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LLC","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Antibody","year":"2023","type":"Public Offering","leadProduct":"Axatilimab","moa":"CSF-1R","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Goldman Sachs & Co. LLC","highestDevelopmentStatusID":"8","companyTruncated":"Syndax Pharmaceuticals \/ Goldman Sachs & Co. LLC"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Incyte Corporation","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Collaboration","leadProduct":"Axatilimab","moa":"CSF-1R","graph1":"Immunology","graph2":"Approved FDF","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Incyte Corporation","highestDevelopmentStatusID":"15","companyTruncated":"Syndax Pharmaceuticals \/ Incyte Corporation"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Goldman Sachs & Co.","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"Revumenib","moa":"||Menin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Syndax Pharmaceuticals \/ Goldman Sachs & Co.","highestDevelopmentStatusID":"7","companyTruncated":"Syndax Pharmaceuticals \/ Goldman Sachs & Co."},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Goldman Sachs & Co. LLC","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2022","type":"Public Offering","leadProduct":"Axatilimab","moa":"CSF-1R","graph1":"Immunology","graph2":"Approved FDF","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Goldman Sachs & Co. LLC","highestDevelopmentStatusID":"15","companyTruncated":"Syndax Pharmaceuticals \/ Goldman Sachs & Co. LLC"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Citigroup","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Public Offering","leadProduct":"Entinostat","moa":"||HDAC","graph1":"Oncology","graph2":"Phase III","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Syndax Pharmaceuticals \/ Citigroup","highestDevelopmentStatusID":"10","companyTruncated":"Syndax Pharmaceuticals \/ Citigroup"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Incyte Corporation","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Collaboration","leadProduct":"Axatilimab","moa":"CSF-1R","graph1":"Immunology","graph2":"Approved FDF","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Incyte Corporation","highestDevelopmentStatusID":"15","companyTruncated":"Syndax Pharmaceuticals \/ Incyte Corporation"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"Axatilimab","moa":"CSF-1R","graph1":"Immunology","graph2":"Approved FDF","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Syndax Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Revumenib","moa":"MLL1-menin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Syndax Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Syndax Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Revumenib","moa":"||Menin","graph1":"Oncology","graph2":"Approved FDF","graph3":"Syndax 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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Revumenib","moa":"||Menin","graph1":"Oncology","graph2":"Approved FDF","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Syndax Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Syndax Pharmaceuticals \/ Inapplicable"}]

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01

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Not Confirmed

Details : Revuforj (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of adult and pediatric patients with relapsed/refractory KMT2A-rearranged (KMT2Ar) acute leukemia.

Product Name : Revuforj

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

December 09, 2024

Lead Product(s) : Revumenib,Cobicistat

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

AAN
Not Confirmed
AAN
Not Confirmed

Details : Revuforj (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of adult and pediatric patients with relapsed/refractory KMT2A-rearranged (KMT2Ar) acute leukemia.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

November 15, 2024

Lead Product(s) : Revumenib,Cobicistat

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

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Not Confirmed
AAN
Not Confirmed

Details : SNDX-5613 (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of adult and pediatric patients with relapsed/refractory KMT2A-rearranged (KMT2Ar) acute leukemia.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

July 29, 2024

Lead Product(s) : Revumenib,Cobicistat

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

AAN
Not Confirmed
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Not Confirmed

Details : SNDX-5613 (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of Relapsed/Refractory metastatic microsatellite stable (MSS) colorectal cancer.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

June 06, 2024

Lead Product(s) : Revumenib

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

AAN
Not Confirmed
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Not Confirmed

Details : The net proceeds will aims to support the planned launches and fund the continued development of Niktimvo (axatilimab) fot the new treatment option for patients with chronic graft-versus-host disease.

Product Name : SNDX-6352

Product Type : Antibody

Upfront Cash : $350.0 million

April 11, 2024

Lead Product(s) : Axatilimab

Therapeutic Area : Immunology

Highest Development Status : Approved FDF

Sponsor : Royalty Pharma

Deal Size : Undisclosed

Deal Type : Agreement

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06

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Not Confirmed
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Not Confirmed

Details : SNDX-5613 (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of Relapsed/Refractory mNPM1 Acute Myeloid Leukemia.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

March 28, 2024

Lead Product(s) : Revumenib,Cobicistat

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

AAN
Not Confirmed
AAN
Not Confirmed

Details : SNDX-5613 (revumenib) is a highly selective, first-in-class oral menin inhibitor, for the treatment of adult and pediatric patients with relapsed or refractory KMT2A-rearranged acute leukemia.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

March 26, 2024

Lead Product(s) : Revumenib,Cobicistat

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

AAN
Not Confirmed
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Not Confirmed

Details : The net proceeds will be used for the ongoing and expanded clinical development of SNDX-6352 (axatilimab) and revumenib, expenses related to the potential U.S. commercial launch of axatilimab in patients with cGVHD and revumenib in defined subsets of acu...

Product Name : SNDX-6352

Product Type : Antibody

Upfront Cash : Undisclosed

December 19, 2023

Lead Product(s) : Axatilimab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Goldman Sachs & Co.

Deal Size : $230.0 million

Deal Type : Public Offering

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09

AAN
Not Confirmed
AAN
Not Confirmed

Details : The net proceeds will fund the ongoing and expanded clinical development of axatilimab and revumenib and expenses related to the potential U.S. commercial launch of axatilimab in patients with cGVHD and revumenib in defined subsets of acute leukemias pat...

Product Name : SNDX-6352

Product Type : Antibody

Upfront Cash : Undisclosed

December 14, 2023

Lead Product(s) : Axatilimab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Goldman Sachs & Co. LLC

Deal Size : $200.0 million

Deal Type : Public Offering

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10

AAN
Not Confirmed
AAN
Not Confirmed

Details : SNDX-5613 (revumenib) is a highly selective, oral menin inhibitor which is under phase 1 clinical development for the treatment of patients with Acute Leukemias.

Product Name : SNDX-5613

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

November 12, 2023

Lead Product(s) : Revumenib,Azacitidine

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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