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Find Clinical Drug Pipeline Developments & Deals by SynOx Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The proceeds are supporting Phase 3 of RG-7155 (emactuzumab), a potentially best-in-class CSF-1 receptor inhibiting monoclonal antibody for the treatment of Tenosynovial Giant Cell Tumour.

                          Brand Name : RG-7155

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 30, 2024

                          Lead Product(s) : Emactuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Gilde Healthcare

                          Deal Size : $92.0 million

                          Deal Type : Series B Financing

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The financing is intended to support the clinical development of Synox's late-stage product and the commercialization of emactuzumab for treating Tenosynovial Giant Cell Tumor.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 30, 2024

                          Lead Product(s) : Emactuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Hercules Capital

                          Deal Size : $75.0 million

                          Deal Type : Series B Financing

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The proceeds will be used to advance late-stage product Emactuzumab, SynOx's potentially best-in-class CSF-1(R) inhibiting monoclonal antibody for the treatment of Tenosynovial Giant Cell Tumour.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 22, 2024

                          Lead Product(s) : Emactuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Forbion

                          Deal Size : $75.0 million

                          Deal Type : Series B Financing

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Emactuzumab is a novel monoclonal antibody inhibiting CSF-1R that offers a short course of treatment. Phase I/II studies indicated good tolerability and a manageable safety profile and substantial preliminary efficacy in TGCT patients.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 31, 2022

                          Lead Product(s) : Emactuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The financing will enable SynOx to continue the development of emactuzumab, for the treatment of diffuse tenosynovial giant cell tumours (“TGCT”), also known as pigmented villonodular synovitis (”PVNS”), and other indications.

                          Brand Name : CXD301

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 19, 2020

                          Lead Product(s) : Emactuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Healthcaps India

                          Deal Size : $45.0 million

                          Deal Type : Series A Financing

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