Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BBI-355,Futibatinib
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Boundless Bio
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, Taiho will provide futibatinib for Boundless Bio’s ongoing Phase 1/2 clinical trial, which will assess BBI-355 in combination with certain selected targeted therapies, including futibatinib, in patients with specific oncogene ampli...
Brand Name : BBI-355
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 18, 2023
Lead Product(s) : BBI-355,Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Boundless Bio
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : CLN-081,Pemetrexed,Cisplatin
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TAS6417 (zipalertinib) is an orally available small molecule designed to target activating mutations in EGFR. The molecule was engineered to inhibit EGFR variants with exon 20 insertion mutations, while sparing wild-type EGFR.
Brand Name : TAS6417
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 03, 2023
Lead Product(s) : CLN-081,Pemetrexed,Cisplatin
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lonsurf (trifluridine/tipiracil), an oral nucleoside antitumor agent, got approved as a single agent or in combination with bevacizumab for the treatment of adult patients with metastatic colorectal cancer (mCRC).
Brand Name : Lonsurf
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 02, 2023
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lytgobi (futibatinib) is a small molecule kinase inhibitor of FGFR 1, 2, 3, and 4. It has demostrated anti-tumour activity by inhibiting FGFR phosphorylation and downstream signaling and decreased cell viability in cancer cell lines with FGFR alterations...
Brand Name : Lytgobi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 04, 2023
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CHMP Issues Positive Opinion for Futibatinib for The Treatment of Adults with Cholangiocarcinoma
Details : TAS-120 (futibatinib) is an oral, potent, selective, and irreversible tyrosine kinase inhibitor of FGFR1, 2, 3 and 4 being studied as a potential treatment for patients with advanced solid tumors with FGFR1-4 genetic aberrations, including cholangiocarci...
Brand Name : TAS-120
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 27, 2023
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lonsurf consists of a thymidine-based nucleoside analog, trifluridine, and the thymidine phosphorylase inhibitor, tipiracil, it has demonstrated anti-tumor activity against refractory colorectal cancer, in combination with bevacizumab.
Brand Name : Lonsurf
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2023
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lytgobi (futibatinib) is a small molecule kinase inhibitor of FGFR 1, 2, 3, and 4. It has demostrated anti-tumour activity by inhibiting FGFR phosphorylation and downstream signaling and decreased cell viability in cancer cell lines with FGFR alterations...
Brand Name : Lytgobi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 18, 2023
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Servier
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lonsurf is an oral nucleoside antitumor agent which consists trifluridine, and tipiracil (TP inhibitor), which increases trifluridine exposure by inhibiting its metabolism by TP. Trifluridine results in DNA dysfunction and inhibition of cell proliferatio...
Brand Name : Lonsurf
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 17, 2023
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Servier
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved
Recipient : Servier
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lonsurf (trifluridine) and tipiracil consists of a thymidine-based nucleoside analog, trifluridine, and the thymidine phosphorylase (TP) inhibitor, tipiracil, which increases trifluridine exposure by inhibiting its metabolism by TP.
Brand Name : Lonsurf
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 12, 2022
Lead Product(s) : Trifluridine,Tipiracil Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Servier
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Key presentations include: Primary results of phase 2 FOENIX-CCA2: the irreversible FGFR1-4 inhibitor futibatinib in intrahepatic cholangiocarcinoma with FGFR2 fusions/rearrangements: Acquired resistance to ATP-competitive and irreversible FGFR inhibitor...
Brand Name : TAS-120
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 02, 2021
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?