Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BioXcel Receives FDA Fast Track Designation for BXCL701 in Prostate Cancer
Details : BXCL701 (talabostat mesylate) is an oral small molecule DPP inhibitor under investigation for small cell neuroendocrine prostate cancer treatment.
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 12, 2024
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BioXcel Completes Enrollment in Safety Portion Of Phase 2 Trial for BXCL701 and KEYTRUDA®
Details : BXCL701 (talabostat mesylate) is an oral innate immune activator evaluated in phase 2 clinical trials in combination with Keytruda for treating metastatic pancreatic ductal adenocarcinoma.
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 06, 2024
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 (talabostat mesylate) is an investigational, oral innate immune activator designed to initiate inflammation in the tumor microenvironment. it is currently being developed for combination with (pembrolizumab) in patients with mCRPC of Adenocarcino...
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 08, 2023
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 (talabostat mesylate) is an investigational, oral innate immune activator designed to initiate inflammation in the tumor microenvironment. it is currently being developed for combination with (pembrolizumab) in patients with small cell neuroendoc...
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 10, 2023
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 (talabostat mesylate) is an investigational, oral innate immune activator designed to initiate inflammation in the tumor microenvironment. BXCL701 is currently being developed for aggressive forms of prostate cancer and advanced solid tumors.
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2023
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 (talabostat mesylate) is an investigational, oral innate immune activator designed to initiate inflammation in the tumor microenvironment. BXCL701 is currently being developed for aggressive forms of prostate cancer and advanced solid tumors.
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 08, 2023
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 is an investigational, oral innate immune activator designed to initiate inflammation in the tumor microenvironment. BXCL701 is currently being developed as a potential therapy for the treatment of aggressive forms of prostate cancer and advanced...
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 11, 2023
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 is an investigational orally administered innate immune activator designed to initiate inflammation in tumor microenvironment, is being evaluated in combination with KEYTRUDA in an ongoing Phase 2 trial in mCRPC patients with either adenocarcinom...
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 19, 2022
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 (talabostat mesylate), investigational orally administered innate immune activator plus KEYTRUDA (pembrolizumab) demonstrates encouraging composite response rates in SCNC (33%) and adenocarcinoma (21%) cohorts.
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 14, 2022
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BXCL701 plus KEYTRUDA® (pembrolizumab) demonstrates encouraging anti-tumor activity in heavily pre-treated mCRPC patients with adenocarcinoma. BXCL701 is orally administered innate immune activator designed to initiate inflammation in tumor microenviron...
Brand Name : BXCL701
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 15, 2021
Lead Product(s) : Talabostat Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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