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Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"AnHeart Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Small molecule","year":"2020","type":"Series A Financing","leadProduct":"Taletrectinib","moa":"ROS1","graph1":"Oncology","graph2":"Phase II","graph3":"AnHeart Therapeutics","amount2":0.02,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.02,"dosageForm":"","sponsorNew":"AnHeart Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"AnHeart Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"AnHeart Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Taletrectinib","moa":"ROS1","graph1":"Oncology","graph2":"Phase II","graph3":"AnHeart 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Bio \/ Sagard Healthcare Partners"}]

Find Clinical Drug Pipeline Developments & Deals for Taletrectinib

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                          Top Deals by Deal Size (USD bn)

                          01

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The financing is intended to support the clinical development and commercialization of AB-106 (taletrectinib), in the U.S. Currently, it is being evaluated for the treatment of ROS1-positive NSCLC.

                          Product Name : AB-106

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 03, 2025

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Sagard Healthcare Partners

                          Deal Size : $250.0 million

                          Deal Type : Financing

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                          02

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : AB-106 (taletrectinib adipate) is a next-generation ROS1 TKI, which is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                          Product Name : AB-106

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 03, 2025

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Dovbleron (taletrectinib) is a next-generation ROS1 TKI, which is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                          Product Name : Dovbleron

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 06, 2025

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : AB-106 (taletrectinib) is a next-generation ROS1 TKI, which is being evaluated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 23, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Dovbleron (taletrectinib) is a next-generation ROS1 TKI, indicated for the treatment of adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 20, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : AB-106 (taletrectinib) is a next-generation ROS1 TKI, which is being evaluated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                          Product Name : AB-106

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 14, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The acquisition adds AnHeart’s AB-106, a next-generation ROS1 inhibitor with Breakthrough Therapy Designations, currently completing two pivotal studies for ROS1-positive non-small cell lung cancer.

                          Product Name : AB-106

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 10, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Nuvation Bio

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          08

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The acquisition adds AnHeart’s AB-106, a next-generation ROS1 inhibitor with Breakthrough Therapy Designations, currently completing two pivotal studies for ROS1-positive non-small cell lung cancer.

                          Product Name : AB-106

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 25, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Nuvation Bio

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          09

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : AB-106 (taletrectinib) is a next-generation ROS1 TKI evaluated for treating adults with advanced or metastatic ROS1-positive non-small cell lung cancer.

                          Product Name : AB-106

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 04, 2024

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Innovent Biologics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : AB-106 (taletrectinib) is a next-generation ROS1 tyrosine kinase inhibitor (TKI), which is under phase 2 clinical development for the treatment of adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC).

                          Product Name : AB-106

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 18, 2023

                          Lead Product(s) : Taletrectinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Innovent Biologics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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