Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Apricoxib,Stimulon
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Agenus
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration with Targovax, Agenus will supply QS-21 STIMULON and scientific support for up to three initial TG01 clinical trials in different cancer indications.
Brand Name : TG01
Molecule Type : Vaccine
Upfront Cash : Undisclosed
March 07, 2022
Lead Product(s) : Apricoxib,Stimulon
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Agenus
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Apricoxib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Innovation Norway
Deal Size : $0.9 million
Deal Type : Funding
Innovation Norway Awards NOK 8.2 mn Grant to Targovax for Development of TG Mutant RAS Vaccine
Details : With the support from Innovation Norway, Targovax has move the TG program forward faster and more broadly, and thus bring benefit to a patient group with poor prognosis and few available treatment options.
Brand Name : TG01
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 12, 2022
Lead Product(s) : Apricoxib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Innovation Norway
Deal Size : $0.9 million
Deal Type : Funding
Lead Product(s) : ONCOS-102,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Targovax Granted European Patent for ONCOS-102 in Combination with Chemotherapy
Details : The patent covers the use of ONCOS-102 in combination with chemotherapy in malignant pleural mesothelioma. ONCOS-102, is a genetically modified oncolytic adenovirus, which has been engineered to selectively infect cancer cells and activate the immune sys...
Brand Name : ONCOS-102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 24, 2021
Lead Product(s) : ONCOS-102,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ONCOS-102,Pembrolizumab,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
US FDA Grants Fast Track Status To Targovax ONCOS-102 to Treat Refractory Advanced Melanoma
Details : The US FDA has granted Fast Track designation to ONCOS-102 based on the current pre-clinical and clinical data package, including mechanistic evidence showing an association between ONCOS-102-induced immune activation and tumor responses.
Brand Name : ONCOS-102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 24, 2021
Lead Product(s) : ONCOS-102,Pembrolizumab,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Targovax Releases Presentations of ONCOS-102 Mesothelioma 24-Month Data
Details : ONCOS-102, an immune activators used in combination with Standard of Care (SoC) chemotherapy in patients with malignant pleural mesothelioma clearly shown tumor responses and survival outcomes.
Brand Name : ONCOS-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 14, 2021
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Targovax’s ONCOS-102 Mesothelioma 24-month Data Shows Class-leading Median Overall Survival
Details : The study is an open-label, exploratory phase 1/2 trial adding ONCOS-102 to SoC chemotherapy (pemetrexed/cisplatin) in first- and second- (or later) line MPM to assess safety, immune activation and clinical efficacy compared with SoC alone.
Brand Name : ONCOS-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 10, 2021
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Theradex
Deal Size : Not Applicable
Deal Type : Not Applicable
Continued Survival Benefit in Targovax’s ONCOS-102 Trial in Mesothelioma at the 21-Month Follow-Up
Details : The trial is an open label, exploratory phase I/II trial adding ONCOS-102 to standard of care (SoC) chemotherapy (pemetrexed/cisplatin) in first and second (and later) line MPM to assess safety, immune activation and clinical efficacy vs SoC only.
Brand Name : ONCOS-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 23, 2021
Lead Product(s) : ONCOS-102,Carboplatin,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Theradex
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Apricoxib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : IOVaxis Therapeutics
Deal Size : $3.0 million
Deal Type : Licensing Agreement
Details : Targovax has granted an extension of 3 months to the exclusive option agreement with IOVaxis Therapeutics of Nantong, China, for clinical development and licensing of the Targovax mutant RAS vaccines TG01 and TG02 in China, Hong Kong, Macau and Singapore...
Brand Name : TG01
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 06, 2021
Lead Product(s) : Apricoxib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : IOVaxis Therapeutics
Deal Size : $3.0 million
Deal Type : Licensing Agreement
Lead Product(s) : ONCOS-102,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Targovax Demonstrates Encouraging Survival Data for ONCOS-102 in Mesothelioma
Details : An 18-month analysis shows that median Overall Survival (mOS) will be at least 18.2 months for first-line patients receiving ONCOS-102 plus chemotherapy, compared to mOS of 14.2 months or less in the chemotherapy-only control group.
Brand Name : ONCOS-102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 24, 2020
Lead Product(s) : ONCOS-102,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ONCOS-102,Durvalumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study is a phase I/II trial assessing the combination of intra-peritoneally delivered ONCOS-102 in combination with systemically administered durvalumab, in patients with colorectal or platinum-resistant ovarian cancers that have metastasized to the ...
Brand Name : ONCOS-102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 13, 2020
Lead Product(s) : ONCOS-102,Durvalumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
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