Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PI3K Miniature Drug Conjugates
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : SciClone
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Tarveda and SciClone’s licensing agreement will permit SciClone to develop, manufacture and commercialize a preclinical-stage product portfolio of miniature drug conjugates that consist of a PI3K inhibitor payload moiety, a linker and HSP90 binding moi...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 16, 2021
Lead Product(s) : PI3K Miniature Drug Conjugates
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : SciClone
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : T-2143
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data from the study show that by leveraging the preferential accumulation of HSP90 targeted conjugates and its payload in tumors, T-2143 can selectively target a pan-PI3K inhibitor, leading to efficacy in multiple xenograft tumor models.
Brand Name : T-2143
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 04, 2020
Lead Product(s) : T-2143
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PEN-866 demonstrates a favorable therapeutic index with a broad therapeutic range, was well tolerated and showed evidence of anti-tumor activity in patients with advanced solid tumor malignancies.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 13, 2020
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PEN-866, a miniature drug conjugate composed of 7-ethyl-10-hydroxy-camptothecin (SN-38) conjugated, through heat shock protein 90 (Hsp90) for treatment of solid tumors.
Brand Name : PEN-866
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 21, 2020
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Organovo Holdings
Deal Size : Undisclosed
Deal Type : Termination
Tarveda Therapeutics Provides Update on Proposed Merger with Organovo
Details : Unanticipated late opposition by major Organovo stockholder results in termination of proposed merger agreement.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 07, 2020
Lead Product(s) : Locnartecan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Organovo Holdings
Deal Size : Undisclosed
Deal Type : Termination
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