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Fidelity Management & Research Company"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"Abeona Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2020","type":"Licensing Agreement","leadProduct":"ABO-202","moa":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"Taysha Gene Therapies","amount2":0.059999999999999998,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":0.059999999999999998,"dosageForm":"","sponsorNew":"Taysha Gene Therapies \/ Taysha Gene Therapies","highestDevelopmentStatusID":"5","companyTruncated":"Taysha Gene Therapies \/ Taysha Gene Therapies"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"TSHA-101","moa":"","graph1":"Genetic 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"TSHA-101","moa":"HEXA gene","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Taysha Gene Therapies","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intrathecal Injection","sponsorNew":"Taysha Gene Therapies \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Taysha Gene Therapies \/ Not Applicable"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"GeneDx","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"TSHA-120","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Taysha Gene Therapies","amount2":0,"highestDevelopmentShortName":"Ph 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\/ RA Capital Management"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"GordonMD Global Investments","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2023","type":"Private Placement","leadProduct":"TSHA-102","moa":"","graph1":"Rare Diseases and Disorders","graph2":"Phase I\/ Phase II","graph3":"Taysha Gene Therapies","amount2":0.14999999999999999,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rare Diseases","amount2New":0.14999999999999999,"dosageForm":"Injectable\/Injection","sponsorNew":"Taysha Gene Therapies \/ GordonMD Global Investments","highestDevelopmentStatusID":"7","companyTruncated":"Taysha Gene Therapies \/ GordonMD Global Investments"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2023","type":"Not 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Jefferies","highestDevelopmentStatusID":"7","companyTruncated":"Taysha Gene Therapies \/ Jefferies"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Public Offering","leadProduct":"TSHA-102","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Taysha Gene Therapies","amount2":0.080000000000000002,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"Taysha Gene Therapies \/ Jefferies","highestDevelopmentStatusID":"7","companyTruncated":"Taysha Gene Therapies \/ Jefferies"},{"orgOrder":0,"company":"Taysha Gene Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"TSHA-102","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Taysha Gene Therapies","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"Taysha Gene Therapies \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Taysha Gene Therapies \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Taysha Gene Therapies

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                          01

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The net proceeds will be used to fund the ongoing clinical, regulatory, and manufacturing development of TSHA-102 for the treatment patients suffering from Rett syndrome.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 26, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Jefferies

                          Deal Size : $75.0 million

                          Deal Type : Public Offering

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The net proceeds will be used to fund the ongoing clinical, regulatory, and manufacturing development of TSHA-102 for the treatment patients suffering from Rett syndrome.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 25, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Jefferies

                          Deal Size : $75.0 million

                          Deal Type : Public Offering

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is a MECP2 modulator, cell & gene therapy candidate, which is being evaluated for the treatment adult and pediatric patients suffering from Rett syndrome.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 18, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is an investigational AAV9 gene transfer therapy using miRARE technology for MECP2 levels in the CNS, under development for Rett Syndrome treatment.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 02, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is a gene transfer therapy using AAV9, designed to mediate MECP2 levels in the CNS, currently under clinical development for Rett Syndrome.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 29, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is an investigational gene transfer therapy using AAV9 and novel miRARE technology to mediate MECP2 levels in the CNS, under phase 1/2 development for Rett Syndrome.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 10, 2024

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is a MECP2 expression regulator cell and gene therapy drug candidate, undergoing evaluation for patients aged 12 and older with Rett syndrome, administered via intrathecal injection.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 29, 2023

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is a self-complementary intrathecally delivered AAV9 investigational gene transfer therapy in clinical evaluation for Rett syndrome. TSHA-102 utilizes a novel miRARE platform designed to regulate cellular MECP2 expression.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 26, 2023

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-120 is a clinical-stage AAV9 gene therapy program being developed for the treatment of giant axonal neuropathy, or GAN, which is a rare autosomal recessive disease of the central and peripheral nervous systems caused by loss-of-function gigaxonin ge...

                          Brand Name : TSHA-120

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 19, 2023

                          Lead Product(s) : TSHA-120

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TSHA-102 is a self-complementary intrathecally delivered AAV9 investigational gene transfer therapy in clinical evaluation for Rett syndrome. TSHA-102 utilizes a novel miRARE platform designed to regulate cellular MECP2 expression.

                          Brand Name : TSHA-102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 24, 2023

                          Lead Product(s) : TSHA-102

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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