Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $5.0 million
Deal Type : Public Offering
GRI Bio Closes $5M Public Offering for Growth and Expansion
Details : The net procceds from the offering will used to advance the clinical development of GRI-0621 (tazarotene), which is being evaluated for idiopathic pulmonary fibrosis.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 02, 2025
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $5.0 million
Deal Type : Public Offering
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $5.0 million
Deal Type : Public Offering
GRI Bio Announces Pricing of $5.0 Million Public Offering
Details : The net procceds from the offering will used to advance the clinical development of GRI-0621 (tazarotene), which is being evaluated for idiopathic pulmonary fibrosis.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 01, 2025
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $5.0 million
Deal Type : Public Offering
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GRI Bio Reports Encouraging Results from Phase 2a of GRI-0621 in IPF
Details : GRI-0621 is the company’s small molecule RAR dual agonist that inhibits the activity of human Type 1 Invariant NKT. It is being evaluated for Idiopathic Pulmonary Fibrosis.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 01, 2025
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GRI Bio Receives Approval for Phase 2a Biomarker Study of GRI-0621 in Australia
Details : GRI-0621 is an RAR-βɣ inhibitor small molecule drug candidate, currently being evaluated for treating idiopathic pulmonary fibrosis via oral soft gel capsule.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 26, 2024
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $4.0 million
Deal Type : Public Offering
GRI Bio Announces Pricing of $4 Million Public Offering
Details : The net proceeds will advance GRI's product candidate GRI-0621 (tazarotene), a small molecule RAR-beta gamma dual agonist, which is being evaluated for the idiopathic pulmonary fibrosis.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 27, 2024
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $4.0 million
Deal Type : Public Offering
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GRI Bio Gets MHRA Authorization for Phase 2a Biomarker Study in the U.K
Details : GRI-0621 is a small molecule RAR-βɣ dual agonist that inhibits the activity of human iNKT cells. It is being evaluated in the Phase II clinical trial studies for Idiopathic Pulmonary Fibrosis.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 03, 2024
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GRI-0621, a small molecule that inhibits the activity of human type 1, iNKT cells. It is being evaluated for the treatment of Idiopathic Pulmonary Fibrosis (IPF).
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 27, 2023
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : NIHR Respiratory TRC
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to advance GRI Bio's leading NKT regulation technology and its lead program, GRI-0621, a small molecule RAR-beta gamma dual agonist that inhibits the activity of human type 1, iNKT cells.to treat inflammatory, fibrotic and autoimmu...
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 17, 2023
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : NIHR Respiratory TRC
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GRI-0621 is an iNKT inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of idiopathic pulmonary fibrosis via oral soft gel capsule.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 12, 2023
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Altium Capital
Deal Size : $25.0 million
Deal Type : Financing
Vallon Pharmaceuticals Completes Merger with GRI Bio, Inc.
Details : The net financing will be used to fund the advancement of GRI Bio’s NKT development pipeline, including GRI-0621, an inhibitor of type 1 NKT cells, targeting multiple inflammatory, fibrotic and autoimmune indications.
Product Name : GRI-0621
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 21, 2023
Lead Product(s) : Tazarotene
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Altium Capital
Deal Size : $25.0 million
Deal Type : Financing