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    [{"orgOrder":0,"company":"Hutchmed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"HONG KONG","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Tazemetostat","moa":"EZH2","graph1":"Oncology","graph2":"Phase II","graph3":"Hutchmed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hutchmed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Hutchmed \/ Inapplicable"},{"orgOrder":0,"company":"Hutchmed","sponsor":"Epizyme","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"HONG KONG","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tazemetostat","moa":"EZH2","graph1":"Oncology","graph2":"Approved FDF","graph3":"Hutchmed","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral 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III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Epizyme \/ Jefferies","highestDevelopmentStatusID":"10","companyTruncated":"Epizyme \/ Jefferies"},{"orgOrder":0,"company":"Epizyme","sponsor":"Ipsen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Acquisition","leadProduct":"Tazemetostat","moa":"EZH2","graph1":"Oncology","graph2":"Approved FDF","graph3":"Epizyme","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Epizyme \/ Ipsen","highestDevelopmentStatusID":"15","companyTruncated":"Epizyme \/ Ipsen"},{"orgOrder":0,"company":"Epizyme","sponsor":"Pharmakon Advisors","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small 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Inapplicable"},{"orgOrder":0,"company":"Epizyme","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tazemetostat","moa":"||EZH2","graph1":"Oncology","graph2":"Approved FDF","graph3":"Epizyme","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Epizyme \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Epizyme \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Tazemetostat

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    Tazemetostat

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                            01

                            Hutchmed

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HUTCHMED Wins NMPA Nod for Tazemetostat in R/R Follicular Lymphoma

                            Details : Tazverik (tazemetostat) is a first-in-class methyltransferase inhibitor of EZH2, which is indicated for the treatment of relapsed or refractory follicular lymphoma.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 21, 2025

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Hutchmed

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                            Hutchmed

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HUTCHMED Receives NDA Acceptance & Priority Review for Tazemetostat in Follicular Lymphoma

                            Details : Tazverik (tazemetostat) is a first-in-class methyltransferase inhibitor of EZH2, which is being evaluated for the treatment of relapsed or refractory follicular lymphoma.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 07, 2024

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Hutchmed

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HUTCHMED Completes Patient Enrollment of a Bridging Study of Tazemetostat in Patients with Relapsed/Refractory...

                            Details : TAZVERIK® (tazemetostat) is a methyltransferase inhibitor indicated in the United States for the treatment of relapsed/refractory follicular lymphoma.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 09, 2023

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Eisai

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                            Eisai

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : National Cancer Center

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Eisai Enters Into Agreement With National Cancer Center To Collaborate On Investigator-initiated Clinical Rese...

                            Details : Eisai will provide Tazverik free of charge to the National Cancer Center Hospital as the drug to be used in a clinical trial of Tazemetostat, a first-in-class, oral small molecule inhibitor of the epigenetic enzyme EZH2, for pediatric and AYA patients wi...

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 04, 2023

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : National Cancer Center

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            05

                            Epizyme

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                            Epizyme

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Ipsen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Ipsen Completes Acquisition of Epizyme Expanding Its Portfolio in Oncology

                            Details : Ipsen acquires Epizyme’s lead medicine, Tazverik® (tazemetostat), a first-inclass, chemotherapy-free EZH2a inhibitor, which was granted Accelerated Approval by the U.S. Food and Drug Administration (FDA) in 2020.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 08, 2022

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Ipsen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            06

                            Epizyme

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Ipsen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Ipsen to Acquire Epizyme, Expanding Its Portfolio in Oncology

                            Details : The primary focus of the acquisition is on the lead medicine, Tazverik® (tazemetostat), a first-in-class, chemotherapy-free EZH2[1] inhibitor, which was granted Accelerated Approval by the U.S. Food and Drug Administration (FDA) in 2020.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 27, 2022

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Ipsen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            07

                            Epizyme

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                            Epizyme

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                            Lead Product(s) : Tazemetostat,Lenalidomide

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Epizyme Announces Executive Appointment and Provides Tazemetostat Clinical Update

                            Details : First patient dosed in the randomized portion of symphony-1 (EZH-302), epizyme’s phase 1B/3 confirmatory study of Tazverik (tazemetostat) in combination with rituximab + lenalidomide (R2) for the treatment of follicular lymphoma.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 15, 2022

                            Lead Product(s) : Tazemetostat,Lenalidomide

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Epizyme

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                            Lead Product(s) : Tazemetostat,Lenalidomide

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Epizyme Presents Updates from SYMPHONY-1 Tazemetostat + R2 Combination Study in Relapsed/Refractory Follicular...

                            Details : Treatment with Tazverik (tazemetostat) and R2 was generally well tolerated and the adverse events were consistent with those contained in the prescribing information for both tazemetostat and R2, respectively.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 06, 2022

                            Lead Product(s) : Tazemetostat,Lenalidomide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Epizyme

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                            Epizyme

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                            Lead Product(s) : Tazemetostat,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Jefferies

                            Deal Size : $85.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Epizyme Announces Pricing of Public Offering of Common Stock

                            Details : Epizyme anticipates using the net proceeds from the offering, together with its existing cash, cash equivalents and marketable securities, to fund global development and commercialization costs of tazemetostat outside of Japan.

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 27, 2022

                            Lead Product(s) : Tazemetostat,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Jefferies

                            Deal Size : $85.0 million

                            Deal Type : Public Offering

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                            10

                            Hutchmed

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                            Hutchmed

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                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HUTCHMED Initiates a Bridging Study of Tazemetostat in Patients with Relapsed/Refractory Follicular Lymphoma i...

                            Details : TAZVERIK® (tazemetostat) is a methyltransferase inhibitor indicated in the United States for the treatment of adults and pediatric patients aged 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resecti...

                            Product Name : Tazverik

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 08, 2022

                            Lead Product(s) : Tazemetostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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