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                            Orion Corporation

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Undisclosed

                            Sponsor : Evariste

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Orion and Evariste Collaborate to Design Inhibitors for Undisclosed Target

                            Details : The collaboration will allow Evariste to utilize its innovative Frobenius Discovery platform to design small-molecule inhibitors for a target selected by Orion.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 10, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Undisclosed

                            Sponsor : Evariste

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Isomorphic Labs

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery

                            Sponsor : Thrive Capital

                            Deal Size : $600.0 million

                            Deal Type : Financing

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                            Isomorphic Announces $600 Million funding to Develop Its Next-gen AI Drug Design Engine

                            Details : Isomorphic Labs will utilise the funding to further power its AI drug design engine through frontier AI research and development and to scale and progress its drug candidate pipeline.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 31, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery

                            Sponsor : Thrive Capital

                            Deal Size : $600.0 million

                            Deal Type : Financing

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                            ImmunoPrecise

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : RIBOPRO

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            IPA, RIBOPRO Partner to Advance mRNA Antibody Discovery for Immunotherapy

                            Details : The collaboration seeks to discover and development of therapeutic antibodies by integrating RIBOPRO’s advanced mRNA-based antigen expression expertise with IPA’s in silico and antibody discovery.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            February 26, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : RIBOPRO

                            Deal Size : Undisclosed

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                            Genesis Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Incyte Corporation

                            Deal Size : $325.0 million

                            Deal Type : Collaboration

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                            Incyte and Genesis Therapeutics Announce Strategic AI-focused Research Collaboration

                            Details : The collaboration will focus on researching and developing novel small-molecule medicines by leveraging Genesis’ proprietary AI platform, with an initial emphasis on targets selected by Incyte.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $30.0 million

                            February 20, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Incyte Corporation

                            Deal Size : $325.0 million

                            Deal Type : Collaboration

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                            05

                            Variational AI

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                            Variational AI

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Merck Global Health Innovation Fund

                            Deal Size : $15.0 million

                            Deal Type : Financing

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                            Variational AI Raises $5.5M to Launch Drug Discovery Foundation Model

                            Details : The proceeds will be used to efficiently discover and optimize novel hits and leads, accelerating small molecule drug discovery using Enki, an advanced foundation model.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $15.0 million

                            February 20, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Merck Global Health Innovation Fund

                            Deal Size : $15.0 million

                            Deal Type : Financing

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                            06

                            Isomorphic Labs

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                            Isomorphic Labs

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $1,237.5 million

                            Deal Type : Collaboration

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                            Isomorphic Labs Announces Novartis Collaboration Expansion

                            Details : IsoLabs and Novartis will expand the scope of the initial collaboration, adding up to three additional research programs to discover small molecule therapeutics against three undisclosed targets.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $37.5 million

                            February 18, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $1,237.5 million

                            Deal Type : Collaboration

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                            07

                            Alloy Therapeutics

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                            Alloy Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Alloy Collaboration with Pfizer to Develop New Antibody Discovery Platform

                            Details : The collaboration aims to develop a new platform that could enhance Pfizer’s ability to discover antibodies against targets that are difficult to address with existing antibody discovery technologies.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            February 11, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Acellera Therapeutics

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                            Acellera Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Psivant Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Acellera, Psivant Collaborate on AI, Quantum-Driven Drug Discovery Approaches

                            Details : The collaboration aims to develop transformative computation approaches that will accelerate the discovery and optimization of novel small molecule drug candidates.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 29, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Psivant Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            09

                            Tevogen Bio

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                            Tevogen Bio

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Microsoft

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Tevogen Bio Expands AI Collaboration with Microsoft for PredicTcell Technology on Azure

                            Details : Tevogen has collaborates with Microsoft to develop new algorithms for decoding interactions between HLA and T cells, aiming to accelerate target identification and strengthen Tevogen Bio’s pipeline.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 24, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Microsoft

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            Light Horse Therapeutics

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                            Light Horse Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Sponsor : Versant Ventures

                            Deal Size : $62.0 million

                            Deal Type : Series A Financing

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                            Light Horse Therapeutics Debuts with $62 Million Series A Financing

                            Details : The financing is intended to support the company’s discovery platform for small-molecule drug research, utilizing innovative approaches to address the underlying causes and life-threatening diseases.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 09, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Sponsor : Versant Ventures

                            Deal Size : $62.0 million

                            Deal Type : Series A Financing

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