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                          Top Deals by Deal Size (USD bn)

                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Under the terms of the licensing agreement, Rondo has the right to develop and commercialize therapeutic antibodies resulting from the collaboration.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          April 23, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Rondo Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          Jorna Therapeutics

                          Country arrow
                          AACR Annual meeting
                          Not Confirmed

                          Jorna Therapeutics

                          Country arrow
                          AACR Annual meeting
                          Not Confirmed

                          Details : Under the agreement, Jorna will design RNA editing drug sequences using its proprietary protein and RNA generative AI model, which is based on the quantum mechanics-based AI called SkyEngine.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          April 21, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Ono Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration seeks to discover and development of therapeutic antibodies by integrating RIBOPRO’s advanced mRNA-based antigen expression expertise with IPA’s in silico and antibody discovery.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          February 26, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : RIBOPRO

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration will focus on researching and developing novel small-molecule medicines by leveraging Genesis’ proprietary AI platform, with an initial emphasis on targets selected by Incyte.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $30.0 million

                          February 20, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Incyte Corporation

                          Deal Size : $325.0 million

                          Deal Type : Collaboration

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                          05

                          Variational AI

                          Country arrow
                          AACR Annual meeting
                          Not Confirmed

                          Variational AI

                          Country arrow
                          AACR Annual meeting
                          Not Confirmed

                          Details : The proceeds will be used to efficiently discover and optimize novel hits and leads, accelerating small molecule drug discovery using Enki, an advanced foundation model.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $15.0 million

                          February 20, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Merck Global Health Innovation Fund

                          Deal Size : $15.0 million

                          Deal Type : Financing

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : IsoLabs and Novartis will expand the scope of the initial collaboration, adding up to three additional research programs to discover small molecule therapeutics against three undisclosed targets.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $37.5 million

                          February 18, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : $1,237.5 million

                          Deal Type : Collaboration

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                          07

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration aims to develop a new platform that could enhance Pfizer’s ability to discover antibodies against targets that are difficult to address with existing antibody discovery technologies.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          February 11, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Pfizer Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration aims to develop transformative computation approaches that will accelerate the discovery and optimization of novel small molecule drug candidates.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 29, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Psivant Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Tevogen has collaborates with Microsoft to develop new algorithms for decoding interactions between HLA and T cells, aiming to accelerate target identification and strengthen Tevogen Bio’s pipeline.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 24, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Microsoft

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration combines Iktos' AI-driven discovery platform with Cube's NativeMPTM, as well as their purification and assay expertise, to accelerate the development of breakthrough therapies.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 10, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Sponsor : Cube Biotech

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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